6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine structure

6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine

TL;DR: 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine (CAS 16824-50-3) is a chemical compound with molecular formula C14H12F3NO and molecular weight 267.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(4-methylphenoxy)-5-(trifluoromethyl)aniline

Also Known As: 2-(4-methylphenoxy)-5-(trifluoromethyl)aniline, 5-Chlor-2-p-tolyloxy-anilin, 2-(p-Tolyloxy)-5-(trifluoromethyl)aniline, 6-(P-TOLYLOXY)-ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLUIDINE, 653-034-9

CAS: 16824-50-3
Molecular Formula C14H12F3NO
Molecular Weight 267.09 g/mol
LogP 4.38832
Topological Polar Surface Area 35.25 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 2
Exact Mass 267.0871
Heavy Atoms 19
Complexity 576.2352

Chemical Identifiers

CAS Number 16824-50-3
SMILES CC1=CC=C(C=C1)OC2=C(C=C(C=C2)C(F)(F)F)N

Product Overview

6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine (CAS 16824-50-3), with molecular formula C14H12F3NO and molecular weight 267.09 g/mol. IUPAC: 2-(4-methylphenoxy)-5-(trifluoromethyl)aniline.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine

XLogP
4.38832
TPSA (Topological Polar Surface Area)
35.25
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
2
Heavy Atoms
19
Complexity
576.2352
Exact Mass
267.0871
Monoisotopic Mass
267.0871
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine

The XLogP value of 4.38832 indicates that 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.25 Ų, 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine?

The CAS number of 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine is 16824-50-3.

What is the molecular formula of 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine?

The molecular formula of 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine is C14H12F3NO.

What is the molecular weight of 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine?

The molecular weight of 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine is 267.09 g/mol.

Where can I buy 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine?

You can request a quote for 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine?

Yes, KEHONG BIO provides custom synthesis services for 6-(P-Tolyloxy)-alpha,alpha,alpha-trifluoro-M-toluidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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