RefChem:375353
TL;DR: RefChem:375353 (CAS 16785-22-1) is a chemical compound with molecular formula C22H28Cl2N2O4 and molecular weight 454.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[4-(2-chlorophenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)propan-1-one;hydrochloride
Also Known As: 1-(o-Chlorophenyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine hydrochloride, Propiophenone, 3-(4-(o-chlorophenyl)piperazinyl)-3',4',5'-trimethoxy-, hydrochloride, 3-(4-(o-Chlorophenyl)piperazinyl)-3',4',5'-trimethoxypropiophenone hydrochloride, Piperazine, 1-(o-chlorophenyl)-4-(3,4,5-trimethoxybenzoylethyl)-, hydrochloride, 3-[4-(2-chlorophenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)propan-1-one hydrochloride
| Molecular Formula | C22H28Cl2N2O4 |
|---|---|
| Molecular Weight | 454.14 g/mol |
| LogP | 4.1826 |
| Topological Polar Surface Area | 51.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 454.1426 |
| Heavy Atoms | 30 |
| Complexity | 501.0 |
Chemical Identifiers
| CAS Number | 16785-22-1 |
|---|---|
| SMILES | COC1=CC(=CC(=C1OC)OC)C(=O)CCN2CCN(CC2)C3=CC=CC=C3Cl.Cl |
| InChIKey | QRQGXYURGQCVFV-UHFFFAOYSA-N |
Product Overview
RefChem:375353 (CAS 16785-22-1), with molecular formula C22H28Cl2N2O4 and molecular weight 454.14 g/mol. IUPAC: 3-[4-(2-chlorophenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)propan-1-one;hydrochloride.
Chemical Property Profile of RefChem:375353
Property Insights of RefChem:375353
The XLogP value of 4.1826 indicates that RefChem:375353 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.2 Ų, RefChem:375353 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:375353 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:375353?
The CAS number of RefChem:375353 is 16785-22-1.
What is the molecular formula of RefChem:375353?
The molecular formula of RefChem:375353 is C22H28Cl2N2O4.
What is the molecular weight of RefChem:375353?
The molecular weight of RefChem:375353 is 454.14 g/mol.
Where can I buy RefChem:375353?
You can request a quote for RefChem:375353 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:375353?
Yes, KEHONG BIO provides custom synthesis services for RefChem:375353 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.