Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide structure

Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide

TL;DR: Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide (CAS 1666-17-7) is a chemical compound with molecular formula C30H37N7O7S and molecular weight 639.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-N-[(2S)-5-(diaminomethylideneamino)-2-[(4-methyl-2-oxochromen-7-yl)amino]pentanoyl]-1-[2-[(4-methylphenyl)sulfonylamino]acetyl]pyrrolidine-2-carboxamide

Also Known As: Tgpamnh2, Tos-Gly-Pro-Arg-AMC HCl, Tos-gly-pro-arg-4-methylcoumaryl-7-NH2, Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide, N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride

CAS: 1666-17-7
Molecular Formula C30H37N7O7S
Molecular Weight 639.25 g/mol
LogP 1.2
Topological Polar Surface Area 224.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 10
Rotatable Bonds 12
Exact Mass 639.2475
Heavy Atoms 45
Complexity 1270.0

Chemical Identifiers

CAS Number 1666-17-7
SMILES CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)N2CCC[C@H]2C(=O)NC(=O)[C@H](CCCN=C(N)N)NC3=CC4=C(C=C3)C(=CC(=O)O4)C
InChIKey PZPDSUNEHIMSSV-ZEQRLZLVSA-N

Product Overview

Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide (CAS 1666-17-7), with molecular formula C30H37N7O7S and molecular weight 639.25 g/mol. IUPAC: (2S)-N-[(2S)-5-(diaminomethylideneamino)-2-[(4-methyl-2-oxochromen-7-yl)amino]pentanoyl]-1-[2-[(4-methylphenyl)sulfonylamino]acetyl]pyrrolidine-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide

XLogP
1.2
TPSA (Topological Polar Surface Area)
224.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
10
Rotatable Bonds
12
Heavy Atoms
45
Complexity
1270.0
Exact Mass
639.2475
Monoisotopic Mass
639.2475
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide

The XLogP value of 1.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide. The TPSA of 224.0 Ų indicates high polarity, suggesting Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide?

The CAS number of Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide is 1666-17-7.

What is the molecular formula of Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide?

The molecular formula of Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide is C30H37N7O7S.

What is the molecular weight of Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide?

The molecular weight of Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide is 639.25 g/mol.

Where can I buy Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide?

You can request a quote for Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide?

Yes, KEHONG BIO provides custom synthesis services for Tosyl-glycyl-prolyl-arginyl-4-methylcoumaryl-7-amide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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