Naxifylline
TL;DR: Naxifylline (CAS 166374-49-8) is a chemical compound with molecular formula C18H24N4O3 and molecular weight 344.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-[(1S,2S,4R,5S,6S)-3-oxatricyclo[3.2.1.02,4]octan-6-yl]-1,3-dipropyl-7H-purine-2,6-dione
Also Known As: Naxifylline, Adentri, ENX cpd, Naxifylline [USAN:INN], 1,3-ENX
| Molecular Formula | C18H24N4O3 |
|---|---|
| Molecular Weight | 344.18 g/mol |
| LogP | 2.0 |
| Topological Polar Surface Area | 81.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 344.18484 |
| Heavy Atoms | 25 |
| Complexity | 599.0 |
Chemical Identifiers
| CAS Number | 166374-49-8 |
|---|---|
| SMILES | CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)[C@H]3C[C@H]4C[C@@H]3[C@@H]5[C@H]4O5 |
| InChIKey | OQCJPFYWFGUHIN-VSEIDBEKSA-N |
Product Overview
Naxifylline (CAS 166374-49-8), with molecular formula C18H24N4O3 and molecular weight 344.18 g/mol. IUPAC: 8-[(1S,2S,4R,5S,6S)-3-oxatricyclo[3.2.1.02,4]octan-6-yl]-1,3-dipropyl-7H-purine-2,6-dione.
Chemical Property Profile of Naxifylline
Property Insights of Naxifylline
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Naxifylline. The TPSA of 81.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Naxifylline. Following Lipinski's Rule of Five, Naxifylline has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Naxifylline?
The CAS number of Naxifylline is 166374-49-8.
What is the molecular formula of Naxifylline?
The molecular formula of Naxifylline is C18H24N4O3.
What is the molecular weight of Naxifylline?
The molecular weight of Naxifylline is 344.18 g/mol.
Where can I buy Naxifylline?
You can request a quote for Naxifylline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Naxifylline?
Yes, KEHONG BIO provides custom synthesis services for Naxifylline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.