4-Chloro-2'-hydroxy-5'-methylchalcone
TL;DR: 4-Chloro-2'-hydroxy-5'-methylchalcone (CAS 16635-10-2) is a chemical compound with molecular formula C16H13ClO2 and molecular weight 272.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(4-chlorophenyl)-1-(2-hydroxy-5-methylphenyl)prop-2-en-1-one
Also Known As: 4-CHLORO-2'-HYDROXY-5'-METHYLCHALCONE, 3-(4-chlorophenyl)-1-(2-hydroxy-5-methylphenyl)prop-2-en-1-one, 2-Propen-1-one, 3-(4-chlorophenyl)-1-(2-hydroxy-5-methylphenyl)-
| Molecular Formula | C16H13ClO2 |
|---|---|
| Molecular Weight | 272.06 g/mol |
| LogP | 4.25012 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 272.0604 |
| Heavy Atoms | 19 |
| Complexity | 627.6972 |
Chemical Identifiers
| CAS Number | 16635-10-2 |
|---|---|
| SMILES | CC1=CC(=C(C=C1)O)C(=O)C=CC2=CC=C(C=C2)Cl |
Product Overview
4-Chloro-2'-hydroxy-5'-methylchalcone (CAS 16635-10-2), with molecular formula C16H13ClO2 and molecular weight 272.06 g/mol. IUPAC: 3-(4-chlorophenyl)-1-(2-hydroxy-5-methylphenyl)prop-2-en-1-one.
Chemical Property Profile of 4-Chloro-2'-hydroxy-5'-methylchalcone
Property Insights of 4-Chloro-2'-hydroxy-5'-methylchalcone
The XLogP value of 4.25012 indicates that 4-Chloro-2'-hydroxy-5'-methylchalcone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 4-Chloro-2'-hydroxy-5'-methylchalcone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-2'-hydroxy-5'-methylchalcone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Chloro-2'-hydroxy-5'-methylchalcone?
The CAS number of 4-Chloro-2'-hydroxy-5'-methylchalcone is 16635-10-2.
What is the molecular formula of 4-Chloro-2'-hydroxy-5'-methylchalcone?
The molecular formula of 4-Chloro-2'-hydroxy-5'-methylchalcone is C16H13ClO2.
What is the molecular weight of 4-Chloro-2'-hydroxy-5'-methylchalcone?
The molecular weight of 4-Chloro-2'-hydroxy-5'-methylchalcone is 272.06 g/mol.
Where can I buy 4-Chloro-2'-hydroxy-5'-methylchalcone?
You can request a quote for 4-Chloro-2'-hydroxy-5'-methylchalcone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Chloro-2'-hydroxy-5'-methylchalcone?
Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-2'-hydroxy-5'-methylchalcone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.