2',3'-Dideoxy-3'-fluoro-4'-thiouridine
TL;DR: 2',3'-Dideoxy-3'-fluoro-4'-thiouridine (CAS 166249-14-5) is a chemical compound with molecular formula C9H11FN2O3S and molecular weight 246.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione
Also Known As: 2',3'-Dideoxy-3'-fluoro-4'-thiouridine, uridine, 2',3'-dideoxy-3'-fluoro-4'-thio-, 1-(4-Fluoro-5-hydroxymethyl-tetrahydro-thiophen-2-yl)-1H-pyrimidine-2,4-dione, 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrothiophen-2-yl]pyrimidine-2,4-dione, 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione
| Molecular Formula | C9H11FN2O3S |
|---|---|
| Molecular Weight | 246.05 g/mol |
| LogP | -0.1 |
| Topological Polar Surface Area | 94.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 246.04744 |
| Heavy Atoms | 16 |
| Complexity | 350.0 |
Chemical Identifiers
| CAS Number | 166249-14-5 |
|---|---|
| SMILES | C1[C@@H]([C@H](S[C@H]1N2C=CC(=O)NC2=O)CO)F |
| InChIKey | ONBOXRBCMARQFJ-SHYZEUOFSA-N |
Product Overview
2',3'-Dideoxy-3'-fluoro-4'-thiouridine (CAS 166249-14-5), with molecular formula C9H11FN2O3S and molecular weight 246.05 g/mol. IUPAC: 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of 2',3'-Dideoxy-3'-fluoro-4'-thiouridine
Property Insights of 2',3'-Dideoxy-3'-fluoro-4'-thiouridine
The XLogP value of -0.1 indicates that 2',3'-Dideoxy-3'-fluoro-4'-thiouridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 94.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 2',3'-Dideoxy-3'-fluoro-4'-thiouridine. Following Lipinski's Rule of Five, 2',3'-Dideoxy-3'-fluoro-4'-thiouridine has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2',3'-Dideoxy-3'-fluoro-4'-thiouridine?
The CAS number of 2',3'-Dideoxy-3'-fluoro-4'-thiouridine is 166249-14-5.
What is the molecular formula of 2',3'-Dideoxy-3'-fluoro-4'-thiouridine?
The molecular formula of 2',3'-Dideoxy-3'-fluoro-4'-thiouridine is C9H11FN2O3S.
What is the molecular weight of 2',3'-Dideoxy-3'-fluoro-4'-thiouridine?
The molecular weight of 2',3'-Dideoxy-3'-fluoro-4'-thiouridine is 246.05 g/mol.
Where can I buy 2',3'-Dideoxy-3'-fluoro-4'-thiouridine?
You can request a quote for 2',3'-Dideoxy-3'-fluoro-4'-thiouridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2',3'-Dideoxy-3'-fluoro-4'-thiouridine?
Yes, KEHONG BIO provides custom synthesis services for 2',3'-Dideoxy-3'-fluoro-4'-thiouridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.