NK 1145 structure

NK 1145

TL;DR: NK 1145 (CAS 16487-37-9) is a chemical compound with molecular formula C14H20ClNO and molecular weight 253.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

NK 1145

8-methyl-3-phenoxy-8-azabicyclo[3.2.1]octane;hydrochloride

Also Known As: NK-1145 hydrochloride, Phenyl tropan-3alpha-yl ester, NK-1145 hydrocholdoride, NK 1145, Tropine-3-beta-phenyl ether hydrochloride

CAS: 16487-37-9
Molecular Formula C14H20ClNO
Molecular Weight 253.12 g/mol
LogP 3.11
Topological Polar Surface Area 12.5 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 2
Exact Mass 253.12334
Heavy Atoms 17
Complexity 223.0

Chemical Identifiers

CAS Number 16487-37-9
SMILES CN1C2CCC1CC(C2)OC3=CC=CC=C3.Cl
InChIKey QCNBFZDTSBLLIW-UHFFFAOYSA-N

Product Overview

NK 1145 (CAS 16487-37-9), with molecular formula C14H20ClNO and molecular weight 253.12 g/mol. IUPAC: 8-methyl-3-phenoxy-8-azabicyclo[3.2.1]octane;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of NK 1145

XLogP
3.11
TPSA (Topological Polar Surface Area)
12.5
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
2
Heavy Atoms
17
Complexity
223.0
Exact Mass
253.12334
Monoisotopic Mass
253.12334
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of NK 1145

The XLogP value of 3.11 indicates that NK 1145 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.5 Ų, NK 1145 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, NK 1145 has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of NK 1145?

The CAS number of NK 1145 is 16487-37-9.

What is the molecular formula of NK 1145?

The molecular formula of NK 1145 is C14H20ClNO.

What is the molecular weight of NK 1145?

The molecular weight of NK 1145 is 253.12 g/mol.

Where can I buy NK 1145?

You can request a quote for NK 1145 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for NK 1145?

Yes, KEHONG BIO provides custom synthesis services for NK 1145 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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