14-Hydroxyestradiol
TL;DR: 14-Hydroxyestradiol (CAS 16288-09-8) is a chemical compound with molecular formula C18H24O3 and molecular weight 288.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,9S,13R,14R,17S)-13-methyl-7,8,9,11,12,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-3,14,17-triol
Also Known As: 14-Hydroxyestradiol, Estra-1(10),2,4-triene-3,14,17-triol, Estra-1(10),2,4-triene-3,14,17beta-triol, Oestra-1,3,5(10)-trien-3,14, A,17
| Molecular Formula | C18H24O3 |
|---|---|
| Molecular Weight | 288.17 g/mol |
| LogP | 2.7 |
| Topological Polar Surface Area | 60.7 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 288.17255 |
| Heavy Atoms | 21 |
| Complexity | 425.0 |
Chemical Identifiers
| CAS Number | 16288-09-8 |
|---|---|
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@]1(CC[C@@H]2O)O)CCC4=C3C=CC(=C4)O |
| InChIKey | RNAMCOMPBVHJSV-UYTYNIKBSA-N |
Product Overview
14-Hydroxyestradiol (CAS 16288-09-8), with molecular formula C18H24O3 and molecular weight 288.17 g/mol. IUPAC: (8R,9S,13R,14R,17S)-13-methyl-7,8,9,11,12,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-3,14,17-triol.
Chemical Property Profile of 14-Hydroxyestradiol
Property Insights of 14-Hydroxyestradiol
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 14-Hydroxyestradiol. The TPSA of 60.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 14-Hydroxyestradiol. Following Lipinski's Rule of Five, 14-Hydroxyestradiol has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 14-Hydroxyestradiol?
The CAS number of 14-Hydroxyestradiol is 16288-09-8.
What is the molecular formula of 14-Hydroxyestradiol?
The molecular formula of 14-Hydroxyestradiol is C18H24O3.
What is the molecular weight of 14-Hydroxyestradiol?
The molecular weight of 14-Hydroxyestradiol is 288.17 g/mol.
Where can I buy 14-Hydroxyestradiol?
You can request a quote for 14-Hydroxyestradiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 14-Hydroxyestradiol?
Yes, KEHONG BIO provides custom synthesis services for 14-Hydroxyestradiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.