![[(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol structure](/static/products/1609/160963-12-2.webp)
[(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol
TL;DR: [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol (CAS 160963-12-2) is a chemical compound with molecular formula C10H12ClN5OS and molecular weight 285.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2R,5S)-5-(6-amino-2-chloropurin-9-yl)thiolan-2-yl]methanol
Also Known As: 4-Thionucleoside analog, [(2R,5S)-5-(6-amino-2-chloropurin-9-yl)thiolan-2-yl]methanol, [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol, 2 -Chloro-6-amino-9-(2,3-dideoxy-4-thio-.beta.-L-ribofuranosyl)purine, 2-Thiophenemethanol,5-(6-amino-2-chloro-9H-purin-9-yl)tetrahydro-,(2R-cis)-
| Molecular Formula | C10H12ClN5OS |
|---|---|
| Molecular Weight | 285.05 g/mol |
| LogP | 1.6 |
| Topological Polar Surface Area | 115.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 285.0451 |
| Heavy Atoms | 18 |
| Complexity | 312.0 |
Chemical Identifiers
| CAS Number | 160963-12-2 |
|---|---|
| SMILES | C1C[C@H](S[C@H]1CO)N2C=NC3=C(N=C(N=C32)Cl)N |
| InChIKey | FKKJDKODGQMPPN-RITPCOANSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
[(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol (CAS 160963-12-2), with molecular formula C10H12ClN5OS and molecular weight 285.05 g/mol. IUPAC: [(2R,5S)-5-(6-amino-2-chloropurin-9-yl)thiolan-2-yl]methanol.
Chemical Property Profile of [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol
Property Insights of [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol. The TPSA of 115.0 Ų falls within the moderate polarity range, balancing permeability and solubility for [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol. Following Lipinski's Rule of Five, [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol?
The CAS number of [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol is 160963-12-2.
What is the molecular formula of [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol?
The molecular formula of [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol is C10H12ClN5OS.
What is the molecular weight of [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol?
The molecular weight of [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol is 285.05 g/mol.
Where can I buy [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol?
You can request a quote for [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol?
Yes, KEHONG BIO provides custom synthesis services for [(2R,5S)-5-(6-amino-2-chloro-purin-9-yl)tetrahydrothiophen-2-yl]methanol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.