4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid
TL;DR: 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid (CAS 160944-66-1) is a chemical compound with molecular formula C18H15N3O3 and molecular weight 321.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-hydroxyanilino)-6-methyl-2-phenylpyrimidine-5-carboxylic acid
Also Known As: AF-602/30349054, 4-(4-hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid, 4-(4-hydroxyanilino)-6-methyl-2-phenylpyrimidine-5-carboxylic acid, 4-[(4-hydroxyphenyl)amino]-6-methyl-2-phenyl-pyrimidine-5-carboxylic Acid
| Molecular Formula | C18H15N3O3 |
|---|---|
| Molecular Weight | 321.11 g/mol |
| LogP | 3.59942 |
| Topological Polar Surface Area | 95.34 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 321.11133 |
| Heavy Atoms | 24 |
| Complexity | 878.01575 |
Chemical Identifiers
| CAS Number | 160944-66-1 |
|---|---|
| SMILES | CC1=C(C(=NC(=N1)C2=CC=CC=C2)NC3=CC=C(C=C3)O)C(=O)O |
Product Overview
4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid (CAS 160944-66-1), with molecular formula C18H15N3O3 and molecular weight 321.11 g/mol. IUPAC: 4-(4-hydroxyanilino)-6-methyl-2-phenylpyrimidine-5-carboxylic acid.
Chemical Property Profile of 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid
Property Insights of 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid
The XLogP value of 3.59942 indicates that 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.34 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid. Following Lipinski's Rule of Five, 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid?
The CAS number of 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid is 160944-66-1.
What is the molecular formula of 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid?
The molecular formula of 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid is C18H15N3O3.
What is the molecular weight of 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid?
The molecular weight of 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid is 321.11 g/mol.
Where can I buy 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid?
You can request a quote for 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-Hydroxyanilino)-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.