thyrotropin-releasing hormone, 1-(methano-Glp(2,3))-
TL;DR: thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- (CAS 16076-17-8) is a chemical compound with molecular formula C17H22N6O4 and molecular weight 374.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-3-oxo-2-azabicyclo[3.1.0]hexane-1-carboxamide
Also Known As: TRH, 1-(2,3-methano-glp)-, Thyrotropin-releasing hormone, 1-(methano-glp(2,3))-, 1-(2,3-Methano-glp)-thyrotropin-releasing hormone, Thyrotropin-releasing hormone, 1-(methanopyroglutamic acid(2,3))-, n-[(3-oxo-2-azabicyclo[3.1.0]hex-1-yl)carbonyl]-l-histidyl-l-prolinamide
| Molecular Formula | C17H22N6O4 |
|---|---|
| Molecular Weight | 374.17 g/mol |
| LogP | -2.6 |
| Topological Polar Surface Area | 150.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 374.17026 |
| Heavy Atoms | 27 |
| Complexity | 684.0 |
Chemical Identifiers
| CAS Number | 16076-17-8 |
|---|---|
| SMILES | C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)C34CC3CC(=O)N4)C(=O)N |
| InChIKey | MJTKVZDHIBJJAQ-DYVBBLHISA-N |
Product Overview
thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- (CAS 16076-17-8), with molecular formula C17H22N6O4 and molecular weight 374.17 g/mol. IUPAC: N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-3-oxo-2-azabicyclo[3.1.0]hexane-1-carboxamide.
Chemical Property Profile of thyrotropin-releasing hormone, 1-(methano-Glp(2,3))-
Property Insights of thyrotropin-releasing hormone, 1-(methano-Glp(2,3))-
The XLogP value of -2.6 indicates that thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 150.0 Ų indicates high polarity, suggesting thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of thyrotropin-releasing hormone, 1-(methano-Glp(2,3))-?
The CAS number of thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- is 16076-17-8.
What is the molecular formula of thyrotropin-releasing hormone, 1-(methano-Glp(2,3))-?
The molecular formula of thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- is C17H22N6O4.
What is the molecular weight of thyrotropin-releasing hormone, 1-(methano-Glp(2,3))-?
The molecular weight of thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- is 374.17 g/mol.
Where can I buy thyrotropin-releasing hormone, 1-(methano-Glp(2,3))-?
You can request a quote for thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for thyrotropin-releasing hormone, 1-(methano-Glp(2,3))-?
Yes, KEHONG BIO provides custom synthesis services for thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.