L-754394 structure

L-754394

TL;DR: L-754394 (CAS 160729-91-9) is a chemical compound with molecular formula C38H47N5O5 and molecular weight 653.36 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[2,3-b]pyridin-5-ylmethyl)piperazine-2-carboxamide

Also Known As: Compound K, CompoundK, HIV-IN-11, L 754394, L-754394

CAS: 160729-91-9
Molecular Formula C38H47N5O5
Molecular Weight 653.36 g/mol
LogP 3.6131
Topological Polar Surface Area 131.17 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 8
Rotatable Bonds 11
Exact Mass 653.3577
Heavy Atoms 48
Complexity 1702.3816

Chemical Identifiers

CAS Number 160729-91-9
SMILES CC(C)(C)NC(=O)[C@@H]1CN(CCN1C[C@H](C[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H]3[C@@H](CC4=CC=CC=C34)O)O)CC5=CN=C6C(=C5)C=CO6

Product Overview

L-754394 (CAS 160729-91-9), with molecular formula C38H47N5O5 and molecular weight 653.36 g/mol. IUPAC: (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[2,3-b]pyridin-5-ylmethyl)piperazine-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of L-754394

XLogP
3.6131
TPSA (Topological Polar Surface Area)
131.17
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
8
Rotatable Bonds
11
Heavy Atoms
48
Complexity
1702.3816
Exact Mass
653.3577
Monoisotopic Mass
653.3577
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of L-754394

The XLogP value of 3.6131 indicates that L-754394 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 131.17 Ų falls within the moderate polarity range, balancing permeability and solubility for L-754394. Following Lipinski's Rule of Five, L-754394 has 4 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of L-754394?

The CAS number of L-754394 is 160729-91-9.

What is the molecular formula of L-754394?

The molecular formula of L-754394 is C38H47N5O5.

What is the molecular weight of L-754394?

The molecular weight of L-754394 is 653.36 g/mol.

Where can I buy L-754394?

You can request a quote for L-754394 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for L-754394?

Yes, KEHONG BIO provides custom synthesis services for L-754394 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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