(+)-dOTFC
TL;DR: (+)-dOTFC (CAS 160707-70-0) is a chemical compound with molecular formula C8H10FN3O3S and molecular weight 247.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-5-fluoro-1-[(2S,4S)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]pyrimidin-2-one
Also Known As: (+)-dOTFC, (+)-2'-Deoxy-3'-oxa-4'-thio-5-fluorocytidine, 4-amino-5-fluoro-1-[(2S,4S)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]pyrimidin-2-one, 4-amino-5-fluoro-1-[(2s,4s)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]pyrimidin-2(1h)-one, 1-[2alpha-(Hydroxymethyl)-1,3-oxathiolane-4alpha-yl]-5-fluorocytosine
| Molecular Formula | C8H10FN3O3S |
|---|---|
| Molecular Weight | 247.04 g/mol |
| LogP | -0.9 |
| Topological Polar Surface Area | 113.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 247.0427 |
| Heavy Atoms | 16 |
| Complexity | 374.0 |
Chemical Identifiers
| CAS Number | 160707-70-0 |
|---|---|
| SMILES | C1[C@H](S[C@H](O1)CO)N2C=C(C(=NC2=O)N)F |
| InChIKey | PANPMNGUWWTDHB-WDSKDSINSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
(+)-dOTFC (CAS 160707-70-0), with molecular formula C8H10FN3O3S and molecular weight 247.04 g/mol. IUPAC: 4-amino-5-fluoro-1-[(2S,4S)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]pyrimidin-2-one.
Chemical Property Profile of (+)-dOTFC
Property Insights of (+)-dOTFC
The XLogP value of -0.9 indicates that (+)-dOTFC is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 113.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (+)-dOTFC. Following Lipinski's Rule of Five, (+)-dOTFC has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (+)-dOTFC?
The CAS number of (+)-dOTFC is 160707-70-0.
What is the molecular formula of (+)-dOTFC?
The molecular formula of (+)-dOTFC is C8H10FN3O3S.
What is the molecular weight of (+)-dOTFC?
The molecular weight of (+)-dOTFC is 247.04 g/mol.
Where can I buy (+)-dOTFC?
You can request a quote for (+)-dOTFC directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (+)-dOTFC?
Yes, KEHONG BIO provides custom synthesis services for (+)-dOTFC and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.