(D-Ala3)-Dynorphin A (1-11) amide
TL;DR: (D-Ala3)-Dynorphin A (1-11) amide (CAS 160522-58-7) is a chemical compound with molecular formula C64H106N22O12 and molecular weight 1374.84 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
Also Known As: (D-Ala3)-Dynorphin A (1-11) amide, [D-Ala3]dynorphin A(1-11)amide, Linear [D-Ala3]Dyn A-(1-11)NH2, (2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide, H-Tyr-Gly-D-Ala-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2
| Molecular Formula | C64H106N22O12 |
|---|---|
| Molecular Weight | 1374.84 g/mol |
| LogP | -4.6225 |
| Topological Polar Surface Area | 590.77 Ų |
| Hydrogen Bond Donors | 19 |
| Hydrogen Bond Acceptors | 17 |
| Rotatable Bonds | 44 |
| Exact Mass | 1374.836 |
| Heavy Atoms | 98 |
| Complexity | 3033.5872 |
Chemical Identifiers
| CAS Number | 160522-58-7 |
|---|---|
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](C)NC(=O)CNC(=O)[C@H](CC3=CC=C(C=C3)O)N |
Product Overview
(D-Ala3)-Dynorphin A (1-11) amide (CAS 160522-58-7), with molecular formula C64H106N22O12 and molecular weight 1374.84 g/mol. IUPAC: (2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1,6-diamino-1-oxohexan-2-yl]pyrrolidine-2-carboxamide.
Chemical Property Profile of (D-Ala3)-Dynorphin A (1-11) amide
Property Insights of (D-Ala3)-Dynorphin A (1-11) amide
The XLogP value of -4.6225 indicates that (D-Ala3)-Dynorphin A (1-11) amide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 590.77 Ų indicates high polarity, suggesting (D-Ala3)-Dynorphin A (1-11) amide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, (D-Ala3)-Dynorphin A (1-11) amide has 19 hydrogen bond donor(s) and 17 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (D-Ala3)-Dynorphin A (1-11) amide?
The CAS number of (D-Ala3)-Dynorphin A (1-11) amide is 160522-58-7.
What is the molecular formula of (D-Ala3)-Dynorphin A (1-11) amide?
The molecular formula of (D-Ala3)-Dynorphin A (1-11) amide is C64H106N22O12.
What is the molecular weight of (D-Ala3)-Dynorphin A (1-11) amide?
The molecular weight of (D-Ala3)-Dynorphin A (1-11) amide is 1374.84 g/mol.
Where can I buy (D-Ala3)-Dynorphin A (1-11) amide?
You can request a quote for (D-Ala3)-Dynorphin A (1-11) amide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (D-Ala3)-Dynorphin A (1-11) amide?
Yes, KEHONG BIO provides custom synthesis services for (D-Ala3)-Dynorphin A (1-11) amide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.