3-Desmethyl Istradefylline structure

3-Desmethyl Istradefylline

TL;DR: 3-Desmethyl Istradefylline (CAS 160434-48-0) is a chemical compound with molecular formula C19H22N4O4 and molecular weight 370.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1,3-diethyl-8-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-7-methylpurine-2,6-dione

Also Known As: 3-Desmethyl Istradefylline, Istradefylline Impurity 3, 2-Desmethyl Istradefylline, Istradefylline Impurity 43, (E)-1,3-Diethyl-8-(3-hydroxy-4-methoxystyryl)-7-methylxanthine

CAS: 160434-48-0
Molecular Formula C19H22N4O4
Molecular Weight 370.16 g/mol
LogP 1.8211
Topological Polar Surface Area 91.28 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 5
Exact Mass 370.1641
Heavy Atoms 27
Complexity 1151.1968

Chemical Identifiers

CAS Number 160434-48-0
SMILES CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)/C=C/C3=CC(=C(C=C3)OC)O)C

Product Overview

3-Desmethyl Istradefylline (CAS 160434-48-0), with molecular formula C19H22N4O4 and molecular weight 370.16 g/mol. IUPAC: 1,3-diethyl-8-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-7-methylpurine-2,6-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 3-Desmethyl Istradefylline

XLogP
1.8211
TPSA (Topological Polar Surface Area)
91.28
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
5
Heavy Atoms
27
Complexity
1151.1968
Exact Mass
370.1641
Monoisotopic Mass
370.1641
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-Desmethyl Istradefylline

The XLogP value of 1.8211 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-Desmethyl Istradefylline. The TPSA of 91.28 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-Desmethyl Istradefylline. Following Lipinski's Rule of Five, 3-Desmethyl Istradefylline has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-Desmethyl Istradefylline?

The CAS number of 3-Desmethyl Istradefylline is 160434-48-0.

What is the molecular formula of 3-Desmethyl Istradefylline?

The molecular formula of 3-Desmethyl Istradefylline is C19H22N4O4.

What is the molecular weight of 3-Desmethyl Istradefylline?

The molecular weight of 3-Desmethyl Istradefylline is 370.16 g/mol.

Where can I buy 3-Desmethyl Istradefylline?

You can request a quote for 3-Desmethyl Istradefylline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-Desmethyl Istradefylline?

Yes, KEHONG BIO provides custom synthesis services for 3-Desmethyl Istradefylline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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