N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea
TL;DR: N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea (CAS 160383-80-2) is a chemical compound with molecular formula C14H10ClF3N2O2 and molecular weight 330.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(5-chloro-2-hydroxyphenyl)-3-[3-(trifluoromethyl)phenyl]urea
Also Known As: Kinome_784, N-(3-(Trifluoromethyl)phenyl)-N'-(2-hydroxy-5-chlorophenyl)urea, 1-(5-chloro-2-hydroxyphenyl)-3-[3-(trifluoromethyl)phenyl]urea, 1-(5-chloro-2-hydroxyphenyl)-3-(3-trifluoromethylphenyl)urea, 1-(5-chloro-2-hydroxy-phenyl)-3-(3-(trifluoromethyl)phenyl)urea
| Molecular Formula | C14H10ClF3N2O2 |
|---|---|
| Molecular Weight | 330.04 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 61.4 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 330.0383 |
| Heavy Atoms | 22 |
| Complexity | 395.0 |
Chemical Identifiers
| CAS Number | 160383-80-2 |
|---|---|
| SMILES | C1=CC(=CC(=C1)NC(=O)NC2=C(C=CC(=C2)Cl)O)C(F)(F)F |
| InChIKey | KRHJDJMOIKRPNN-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea (CAS 160383-80-2), with molecular formula C14H10ClF3N2O2 and molecular weight 330.04 g/mol. IUPAC: 1-(5-chloro-2-hydroxyphenyl)-3-[3-(trifluoromethyl)phenyl]urea.
Chemical Property Profile of N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea
Property Insights of N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea
The XLogP value of 3.6 indicates that N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.4 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea. Following Lipinski's Rule of Five, N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea?
The CAS number of N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea is 160383-80-2.
What is the molecular formula of N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea?
The molecular formula of N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea is C14H10ClF3N2O2.
What is the molecular weight of N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea?
The molecular weight of N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea is 330.04 g/mol.
Where can I buy N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea?
You can request a quote for N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea?
Yes, KEHONG BIO provides custom synthesis services for N-(5-Chloro-2-hydroxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.