14-Hydroxyprogesterone
TL;DR: 14-Hydroxyprogesterone (CAS 16031-66-6) is a chemical compound with molecular formula C21H30O3 and molecular weight 330.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,9S,10R,13R,17S)-17-acetyl-14-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: 14-Hydroxyprogesterone, 14alpha-Hydroxyprogesterone, 14beta-Hydroxyprogesterone, Progesterone Impurity 40, 14 beta-hydroxyprogesterone
| Molecular Formula | C21H30O3 |
|---|---|
| Molecular Weight | 330.22 g/mol |
| LogP | 2.4 |
| Topological Polar Surface Area | 54.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 330.21948 |
| Heavy Atoms | 24 |
| Complexity | 635.0 |
Chemical Identifiers
| CAS Number | 16031-66-6 |
|---|---|
| SMILES | CC(=O)[C@H]1CCC2([C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O |
| InChIKey | UAMNQIUKJVUQMR-ZIZLOZECSA-N |
Product Overview
14-Hydroxyprogesterone (CAS 16031-66-6), with molecular formula C21H30O3 and molecular weight 330.22 g/mol. IUPAC: (8R,9S,10R,13R,17S)-17-acetyl-14-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 14-Hydroxyprogesterone
Property Insights of 14-Hydroxyprogesterone
The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 14-Hydroxyprogesterone. With a topological polar surface area (TPSA) of 54.4 Ų, 14-Hydroxyprogesterone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 14-Hydroxyprogesterone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 14-Hydroxyprogesterone?
The CAS number of 14-Hydroxyprogesterone is 16031-66-6.
What is the molecular formula of 14-Hydroxyprogesterone?
The molecular formula of 14-Hydroxyprogesterone is C21H30O3.
What is the molecular weight of 14-Hydroxyprogesterone?
The molecular weight of 14-Hydroxyprogesterone is 330.22 g/mol.
Where can I buy 14-Hydroxyprogesterone?
You can request a quote for 14-Hydroxyprogesterone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 14-Hydroxyprogesterone?
Yes, KEHONG BIO provides custom synthesis services for 14-Hydroxyprogesterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.