1,8-Naphthyridin-2(1H)-one
TL;DR: 1,8-Naphthyridin-2(1H)-one (CAS 15936-09-1) is a chemical compound with molecular formula C8H6N2O and molecular weight 146.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1H-1,8-naphthyridin-2-one
Also Known As: 1,8-Naphthyridin-2(1H)-one, naphthyridone, 1H-1,8-naphthyridin-2-one, 8H-1,8-naphthyridin-2-one, hydroxynaphthyridine
| Molecular Formula | C8H6N2O |
|---|---|
| Molecular Weight | 146.05 g/mol |
| LogP | 0.6 |
| Topological Polar Surface Area | 42.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 146.04802 |
| Heavy Atoms | 11 |
| Complexity | 200.0 |
Chemical Identifiers
| CAS Number | 15936-09-1 |
|---|---|
| SMILES | C1=CC2=C(NC(=O)C=C2)N=C1 |
| InChIKey | ZFRUGZMCGCYBRC-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
1,8-Naphthyridin-2(1H)-one (CAS 15936-09-1), with molecular formula C8H6N2O and molecular weight 146.05 g/mol. IUPAC: 1H-1,8-naphthyridin-2-one.
Chemical Property Profile of 1,8-Naphthyridin-2(1H)-one
Property Insights of 1,8-Naphthyridin-2(1H)-one
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1,8-Naphthyridin-2(1H)-one. With a topological polar surface area (TPSA) of 42.0 Ų, 1,8-Naphthyridin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1,8-Naphthyridin-2(1H)-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1,8-Naphthyridin-2(1H)-one?
The CAS number of 1,8-Naphthyridin-2(1H)-one is 15936-09-1.
What is the molecular formula of 1,8-Naphthyridin-2(1H)-one?
The molecular formula of 1,8-Naphthyridin-2(1H)-one is C8H6N2O.
What is the molecular weight of 1,8-Naphthyridin-2(1H)-one?
The molecular weight of 1,8-Naphthyridin-2(1H)-one is 146.05 g/mol.
Where can I buy 1,8-Naphthyridin-2(1H)-one?
You can request a quote for 1,8-Naphthyridin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1,8-Naphthyridin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 1,8-Naphthyridin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.