FR-86521 free base structure

FR-86521 free base

TL;DR: FR-86521 free base (CAS 157436-91-4) is a chemical compound with molecular formula C19H23N9O6S2 and molecular weight 537.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetyl]amino]-3-[[2-(2-hydroxyethyl)-3-iminopyrazol-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Also Known As: FR-86521 free base, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((5-amino-1,2,4-thiadiazol-3-yl)(ethoxyimino)acetyl)amino)-3-((2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl)methyl)-8-oxo-, (6R-(6alpha,7beta(Z)))-, 5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-(((5-AMINO-1,2,4-THIADIAZOL-3-YL)(ETHOXYIMINO)ACETYL)AMINO)-3-((2,3-DIHYDRO-2-(2-HYDROXYETHYL)-3-IMINO-1H-PYRAZOL-1-YL)METHYL)-8-OXO-, (6R-(6.ALPHA.,7.BETA.(Z)))-

CAS: 157436-91-4
Molecular Formula C19H23N9O6S2
Molecular Weight 537.12 g/mol
LogP -1.62553
Topological Polar Surface Area 214.04 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 12
Rotatable Bonds 10
Exact Mass 537.1213
Heavy Atoms 36
Complexity 1312.4708

Chemical Identifiers

CAS Number 157436-91-4
SMILES CCO/N=C(/C1=NSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)CN4C=CC(=N)N4CCO)C(=O)O

Product Overview

FR-86521 free base (CAS 157436-91-4), with molecular formula C19H23N9O6S2 and molecular weight 537.12 g/mol. IUPAC: (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetyl]amino]-3-[[2-(2-hydroxyethyl)-3-iminopyrazol-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of FR-86521 free base

XLogP
-1.62553
TPSA (Topological Polar Surface Area)
214.04
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
12
Rotatable Bonds
10
Heavy Atoms
36
Complexity
1312.4708
Exact Mass
537.1213
Monoisotopic Mass
537.1213
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of FR-86521 free base

The XLogP value of -1.62553 indicates that FR-86521 free base is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 214.04 Ų indicates high polarity, suggesting FR-86521 free base may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, FR-86521 free base has 5 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of FR-86521 free base?

The CAS number of FR-86521 free base is 157436-91-4.

What is the molecular formula of FR-86521 free base?

The molecular formula of FR-86521 free base is C19H23N9O6S2.

What is the molecular weight of FR-86521 free base?

The molecular weight of FR-86521 free base is 537.12 g/mol.

Where can I buy FR-86521 free base?

You can request a quote for FR-86521 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for FR-86521 free base?

Yes, KEHONG BIO provides custom synthesis services for FR-86521 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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