8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine
TL;DR: 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine (CAS 15717-48-3) is a chemical compound with molecular formula C15H21ClN6O4 and molecular weight 384.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-amino-8-chloro-6-piperidin-1-ylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Also Known As: 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine, 2-(2-amino-8-chloro-6-piperidin-1-ylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, 8-Chloro-9-pentofuranosyl-6-(piperidin-1-yl)-1,9-dihydro-2H-purin-2-imine
| Molecular Formula | C15H21ClN6O4 |
|---|---|
| Molecular Weight | 384.13 g/mol |
| LogP | 0.4 |
| Topological Polar Surface Area | 143.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 3 |
| Exact Mass | 384.1313 |
| Heavy Atoms | 26 |
| Complexity | 501.0 |
Chemical Identifiers
| CAS Number | 15717-48-3 |
|---|---|
| SMILES | C1CCN(CC1)C2=NC(=NC3=C2N=C(N3C4C(C(C(O4)CO)O)O)Cl)N |
| InChIKey | OKNDLDOMGCHNRV-UHFFFAOYSA-N |
Product Overview
8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine (CAS 15717-48-3), with molecular formula C15H21ClN6O4 and molecular weight 384.13 g/mol. IUPAC: 2-(2-amino-8-chloro-6-piperidin-1-ylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol.
Chemical Property Profile of 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine
Property Insights of 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine
The XLogP value of 0.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine. The TPSA of 143.0 Ų indicates high polarity, suggesting 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine?
The CAS number of 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine is 15717-48-3.
What is the molecular formula of 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine?
The molecular formula of 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine is C15H21ClN6O4.
What is the molecular weight of 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine?
The molecular weight of 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine is 384.13 g/mol.
Where can I buy 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine?
You can request a quote for 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 8-chloro-9-pentofuranosyl-6-(piperidin-1-yl)-9h-purin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.