Tibrofan
TL;DR: Tibrofan (CAS 15686-72-3) is a chemical compound with molecular formula C11H6Br3NOS and molecular weight 436.77 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4,5-dibromo-N-(4-bromophenyl)thiophene-2-carboxamide
Also Known As: TIBROFAN, Tibrofan (USAN/INN), Tibrofan [USAN:INN], TIBROFAN [USAN], TIBROFAN [INN]
| Molecular Formula | C11H6Br3NOS |
|---|---|
| Molecular Weight | 436.77 g/mol |
| LogP | 5.2 |
| Topological Polar Surface Area | 57.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 438.76996 |
| Heavy Atoms | 17 |
| Complexity | 284.0 |
Chemical Identifiers
| CAS Number | 15686-72-3 |
|---|---|
| SMILES | C1=CC(=CC=C1NC(=O)C2=CC(=C(S2)Br)Br)Br |
| InChIKey | ZLWLKVQCHZSSEL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Tibrofan (CAS 15686-72-3), with molecular formula C11H6Br3NOS and molecular weight 436.77 g/mol. IUPAC: 4,5-dibromo-N-(4-bromophenyl)thiophene-2-carboxamide.
Chemical Property Profile of Tibrofan
Property Insights of Tibrofan
The XLogP value of 5.2 indicates that Tibrofan is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.3 Ų, Tibrofan exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tibrofan has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tibrofan?
The CAS number of Tibrofan is 15686-72-3.
What is the molecular formula of Tibrofan?
The molecular formula of Tibrofan is C11H6Br3NOS.
What is the molecular weight of Tibrofan?
The molecular weight of Tibrofan is 436.77 g/mol.
Where can I buy Tibrofan?
You can request a quote for Tibrofan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tibrofan?
Yes, KEHONG BIO provides custom synthesis services for Tibrofan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.