21-Norrapamycin
TL;DR: 21-Norrapamycin (CAS 156223-31-3) is a chemical compound with molecular formula C50H77NO13 and molecular weight 899.54 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1,17-dihydroxy-11-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-18,29-dimethoxy-14,16,20,22,28,34-hexamethyl-10,35-dioxa-4-azatricyclo[29.3.1.04,8]pentatriaconta-15,23,25,27-tetraene-2,3,9,13,19-pentone
Also Known As: 21-Norrapamycin, (1R,8S,11S,14R,15E,17R,18R,20R,22S,23E,25E,27E,29S,31S,34R)-1,17-Dihydroxy-11-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-18,29-dimethoxy-14,16,20,22,28,34-hexamethyl-10,35-dioxa-4-azatricyclo[29.3.1.04,8]pentatriaconta-15,23,25,27-tetraene-2,3,9,13,19-pentone
| Molecular Formula | C50H77NO13 |
|---|---|
| Molecular Weight | 899.54 g/mol |
| LogP | 5.7 |
| Topological Polar Surface Area | 195.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 13 |
| Rotatable Bonds | 6 |
| Exact Mass | 899.5395 |
| Heavy Atoms | 64 |
| Complexity | 1740.0 |
Chemical Identifiers
| CAS Number | 156223-31-3 |
|---|---|
| SMILES | CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC |
| InChIKey | RUAWAUYKGXTUTF-UHFFFAOYSA-N |
Product Overview
21-Norrapamycin (CAS 156223-31-3), with molecular formula C50H77NO13 and molecular weight 899.54 g/mol. IUPAC: 1,17-dihydroxy-11-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-18,29-dimethoxy-14,16,20,22,28,34-hexamethyl-10,35-dioxa-4-azatricyclo[29.3.1.04,8]pentatriaconta-15,23,25,27-tetraene-2,3,9,13,19-pentone.
Chemical Property Profile of 21-Norrapamycin
Property Insights of 21-Norrapamycin
The XLogP value of 5.7 indicates that 21-Norrapamycin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 195.0 Ų indicates high polarity, suggesting 21-Norrapamycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 21-Norrapamycin has 3 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 21-Norrapamycin?
The CAS number of 21-Norrapamycin is 156223-31-3.
What is the molecular formula of 21-Norrapamycin?
The molecular formula of 21-Norrapamycin is C50H77NO13.
What is the molecular weight of 21-Norrapamycin?
The molecular weight of 21-Norrapamycin is 899.54 g/mol.
Where can I buy 21-Norrapamycin?
You can request a quote for 21-Norrapamycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 21-Norrapamycin?
Yes, KEHONG BIO provides custom synthesis services for 21-Norrapamycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.