Doxazosin methanesulfonate, (R)-
TL;DR: Doxazosin methanesulfonate, (R)- (CAS 156154-38-0) is a chemical compound with molecular formula C24H29N5O8S and molecular weight 547.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methanone;methanesulfonic acid
Also Known As: Doxazosin mesylate, Doxazosin methanesulfonate, (R)-, Lopac-D-9815, Doxazosin Mesylate, (R)-, 1,4-Benzodioxin, piperazine deriv.
| Molecular Formula | C24H29N5O8S |
|---|---|
| Molecular Weight | 547.17 g/mol |
| LogP | 1.2218 |
| Topological Polar Surface Area | 166.64 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 4 |
| Exact Mass | 547.1737 |
| Heavy Atoms | 38 |
| Complexity | 1418.8232 |
Chemical Identifiers
| CAS Number | 156154-38-0 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)[C@H]4COC5=CC=CC=C5O4)N)OC.CS(=O)(=O)O |
Product Overview
Doxazosin methanesulfonate, (R)- (CAS 156154-38-0), with molecular formula C24H29N5O8S and molecular weight 547.17 g/mol. IUPAC: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methanone;methanesulfonic acid.
Chemical Property Profile of Doxazosin methanesulfonate, (R)-
Property Insights of Doxazosin methanesulfonate, (R)-
The XLogP value of 1.2218 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Doxazosin methanesulfonate, (R)-. The TPSA of 166.64 Ų indicates high polarity, suggesting Doxazosin methanesulfonate, (R)- may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Doxazosin methanesulfonate, (R)- has 2 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Doxazosin methanesulfonate, (R)-?
The CAS number of Doxazosin methanesulfonate, (R)- is 156154-38-0.
What is the molecular formula of Doxazosin methanesulfonate, (R)-?
The molecular formula of Doxazosin methanesulfonate, (R)- is C24H29N5O8S.
What is the molecular weight of Doxazosin methanesulfonate, (R)-?
The molecular weight of Doxazosin methanesulfonate, (R)- is 547.17 g/mol.
Where can I buy Doxazosin methanesulfonate, (R)-?
You can request a quote for Doxazosin methanesulfonate, (R)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Doxazosin methanesulfonate, (R)-?
Yes, KEHONG BIO provides custom synthesis services for Doxazosin methanesulfonate, (R)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.