Hyzaar
TL;DR: Hyzaar (CAS 156154-37-9) is a chemical compound with molecular formula C29H31Cl2N9O5S2 and molecular weight 719.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Also Known As: Hyzaar, Losartan/hydrochlorothiazide, [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide, RefChem:923237
| Molecular Formula | C29H31Cl2N9O5S2 |
|---|---|
| Molecular Weight | 719.13 g/mol |
| LogP | 3.9155 |
| Topological Polar Surface Area | 210.87 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 9 |
| Exact Mass | 719.12665 |
| Heavy Atoms | 47 |
| Complexity | 2088.9539 |
Chemical Identifiers
| CAS Number | 156154-37-9 |
|---|---|
| SMILES | CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl.C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl |
Product Overview
Hyzaar (CAS 156154-37-9), with molecular formula C29H31Cl2N9O5S2 and molecular weight 719.13 g/mol. IUPAC: [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide.
Chemical Property Profile of Hyzaar
Property Insights of Hyzaar
The XLogP value of 3.9155 indicates that Hyzaar is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 210.87 Ų indicates high polarity, suggesting Hyzaar may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Hyzaar has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Hyzaar?
The CAS number of Hyzaar is 156154-37-9.
What is the molecular formula of Hyzaar?
The molecular formula of Hyzaar is C29H31Cl2N9O5S2.
What is the molecular weight of Hyzaar?
The molecular weight of Hyzaar is 719.13 g/mol.
Where can I buy Hyzaar?
You can request a quote for Hyzaar directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Hyzaar?
Yes, KEHONG BIO provides custom synthesis services for Hyzaar and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.