1-Methyl-5-(trifluoromethyl)indoline-2-thione
TL;DR: 1-Methyl-5-(trifluoromethyl)indoline-2-thione (CAS 156136-69-5) is a chemical compound with molecular formula C10H8F3NS and molecular weight 231.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-methyl-5-(trifluoromethyl)-3H-indole-2-thione
Also Known As: 1-Methyl-5-(trifluoromethyl)indoline-2-thione, 1-methyl-5-(trifluoromethyl)-3H-indole-2-thione, 2H-Indole-2-thione, 1,3-dihydro-1-methyl-5-(trifluoromethyl)-, 2H-Indole-2-thione, 1,3-dihydro-1-methyl-5-(trifluoromethyl)-
| Molecular Formula | C10H8F3NS |
|---|---|
| Molecular Weight | 231.03 g/mol |
| LogP | 3.0251 |
| Topological Polar Surface Area | 3.24 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 231.03296 |
| Heavy Atoms | 15 |
| Complexity | 425.16595 |
Chemical Identifiers
| CAS Number | 156136-69-5 |
|---|---|
| SMILES | CN1C(=S)CC2=C1C=CC(=C2)C(F)(F)F |
Product Overview
1-Methyl-5-(trifluoromethyl)indoline-2-thione (CAS 156136-69-5), with molecular formula C10H8F3NS and molecular weight 231.03 g/mol. IUPAC: 1-methyl-5-(trifluoromethyl)-3H-indole-2-thione.
Chemical Property Profile of 1-Methyl-5-(trifluoromethyl)indoline-2-thione
Property Insights of 1-Methyl-5-(trifluoromethyl)indoline-2-thione
The XLogP value of 3.0251 indicates that 1-Methyl-5-(trifluoromethyl)indoline-2-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.24 Ų, 1-Methyl-5-(trifluoromethyl)indoline-2-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Methyl-5-(trifluoromethyl)indoline-2-thione has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-Methyl-5-(trifluoromethyl)indoline-2-thione?
The CAS number of 1-Methyl-5-(trifluoromethyl)indoline-2-thione is 156136-69-5.
What is the molecular formula of 1-Methyl-5-(trifluoromethyl)indoline-2-thione?
The molecular formula of 1-Methyl-5-(trifluoromethyl)indoline-2-thione is C10H8F3NS.
What is the molecular weight of 1-Methyl-5-(trifluoromethyl)indoline-2-thione?
The molecular weight of 1-Methyl-5-(trifluoromethyl)indoline-2-thione is 231.03 g/mol.
Where can I buy 1-Methyl-5-(trifluoromethyl)indoline-2-thione?
You can request a quote for 1-Methyl-5-(trifluoromethyl)indoline-2-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-Methyl-5-(trifluoromethyl)indoline-2-thione?
Yes, KEHONG BIO provides custom synthesis services for 1-Methyl-5-(trifluoromethyl)indoline-2-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.