Dimadectin structure

Dimadectin

TL;DR: Dimadectin (CAS 156131-91-8) is a chemical compound with molecular formula C37H56O10 and molecular weight 660.39 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,16Z,20R,21R,24S)-21,24-dihydroxy-12-(2-methoxyethoxymethoxy)-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one

Also Known As: Dimadectin, Dimadectin [INN], (R)-5-Phenyl-2-(tert-butoxycarbonylamino)pentanoicacid, (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,16Z,20R,21R,24S)-21,24-dihydroxy-12-(2-methoxyethoxymethoxy)-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one, A mixture of (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-(S)-sec-butyl-3',4',5',6,6',7,10,11,14,15,17a,20,20a,20b-tetradecahydro-20,20b-dihydroxy-7-((2-methoxyethoxy)methoxy)-5',6,8,19-tetramethylspiro(11,15-methano-2H,13H,17H-furo(4,3,2-pq)(2,6)benzodioxacyclooctadecin-13,2'-(2H)pyran)-17-one (major component) and (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-3',4',5',6,6',7,10,11,14,15,17a,20,20a,20b-tetradecahydro-20,20b-dihydroxy-6'-isopropyl-7-((2-methoxyethoxy)methoxy)-5',6,8,19-tetramethylspiro(11,15-methano-2H,13H,17H-furo(4,3,2-pq)(2,6)benzodioxacyclooctadecin-13,2'-(2H)pyran)-17-one

CAS: 156131-91-8
Molecular Formula C37H56O10
Molecular Weight 660.39 g/mol
LogP 4.7859
Topological Polar Surface Area 122.14 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 10
Rotatable Bonds 7
Exact Mass 660.3873
Heavy Atoms 47
Complexity 1223.3801

Chemical Identifiers

CAS Number 156131-91-8
SMILES C[C@H]1CC[C@]2(C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)OCOCCOC)/C)O[C@@H]1C(C)C

Product Overview

Dimadectin (CAS 156131-91-8), with molecular formula C37H56O10 and molecular weight 660.39 g/mol. IUPAC: (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,16Z,20R,21R,24S)-21,24-dihydroxy-12-(2-methoxyethoxymethoxy)-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Dimadectin

XLogP
4.7859
TPSA (Topological Polar Surface Area)
122.14
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
10
Rotatable Bonds
7
Heavy Atoms
47
Complexity
1223.3801
Exact Mass
660.3873
Monoisotopic Mass
660.3873
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Dimadectin

The XLogP value of 4.7859 indicates that Dimadectin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 122.14 Ų falls within the moderate polarity range, balancing permeability and solubility for Dimadectin. Following Lipinski's Rule of Five, Dimadectin has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Dimadectin?

The CAS number of Dimadectin is 156131-91-8.

What is the molecular formula of Dimadectin?

The molecular formula of Dimadectin is C37H56O10.

What is the molecular weight of Dimadectin?

The molecular weight of Dimadectin is 660.39 g/mol.

Where can I buy Dimadectin?

You can request a quote for Dimadectin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Dimadectin?

Yes, KEHONG BIO provides custom synthesis services for Dimadectin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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