Ro 41-8568
TL;DR: Ro 41-8568 (CAS 15537-73-2) is a chemical compound with molecular formula C15H14ClF3N2O3 and molecular weight 362.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(4-chloro-3-propan-2-yloxyphenyl)-1-methyl-6-(trifluoromethyl)pyrimidine-2,4-dione
Also Known As: Ro 41-8568, Ro-41-8568, 2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-3-(1-methylethoxy)phenyl)-1-methyl-6-(trifluoromethyl)-, 3-[4-chloro-3-(propan-2-yloxy)phenyl]-1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1h,3h)-dione, 3-(4-Chloro-3-isopropoxyphenyl)-1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione
| Molecular Formula | C15H14ClF3N2O3 |
|---|---|
| Molecular Weight | 362.06 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 49.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 362.0645 |
| Heavy Atoms | 24 |
| Complexity | 551.0 |
Chemical Identifiers
| CAS Number | 15537-73-2 |
|---|---|
| SMILES | CC(C)OC1=C(C=CC(=C1)N2C(=O)C=C(N(C2=O)C)C(F)(F)F)Cl |
| InChIKey | BSHKWHGKJMVVEW-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Ro 41-8568 (CAS 15537-73-2), with molecular formula C15H14ClF3N2O3 and molecular weight 362.06 g/mol. IUPAC: 3-(4-chloro-3-propan-2-yloxyphenyl)-1-methyl-6-(trifluoromethyl)pyrimidine-2,4-dione.
Chemical Property Profile of Ro 41-8568
Property Insights of Ro 41-8568
The XLogP value of 3.2 indicates that Ro 41-8568 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.9 Ų, Ro 41-8568 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ro 41-8568 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ro 41-8568?
The CAS number of Ro 41-8568 is 15537-73-2.
What is the molecular formula of Ro 41-8568?
The molecular formula of Ro 41-8568 is C15H14ClF3N2O3.
What is the molecular weight of Ro 41-8568?
The molecular weight of Ro 41-8568 is 362.06 g/mol.
Where can I buy Ro 41-8568?
You can request a quote for Ro 41-8568 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ro 41-8568?
Yes, KEHONG BIO provides custom synthesis services for Ro 41-8568 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.