Rosiglitazone maleate
TL;DR: Rosiglitazone maleate (CAS 155141-29-0) is a chemical compound with molecular formula C22H23N3O7S and molecular weight 473.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
but-2-enedioic acid;5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Also Known As: Rosiglitazone maleate, 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione; but-2-enedioic acid, 5-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione maleate, (Z)-but-2-enedioic acid;5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, (2Z)-2-butenedioate (1:1)
| Molecular Formula | C22H23N3O7S |
|---|---|
| Molecular Weight | 473.13 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 171.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 9 |
| Exact Mass | 473.12567 |
| Heavy Atoms | 33 |
| Complexity | 587.0 |
Chemical Identifiers
| CAS Number | 155141-29-0 |
|---|---|
| SMILES | CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=CC(=O)O)C(=O)O |
| InChIKey | SUFUKZSWUHZXAV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Rosiglitazone maleate (CAS 155141-29-0), with molecular formula C22H23N3O7S and molecular weight 473.13 g/mol. IUPAC: but-2-enedioic acid;5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of Rosiglitazone maleate
Property Insights of Rosiglitazone maleate
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Rosiglitazone maleate. The TPSA of 171.0 Ų indicates high polarity, suggesting Rosiglitazone maleate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Rosiglitazone maleate has 3 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Rosiglitazone maleate?
The CAS number of Rosiglitazone maleate is 155141-29-0.
What is the molecular formula of Rosiglitazone maleate?
The molecular formula of Rosiglitazone maleate is C22H23N3O7S.
What is the molecular weight of Rosiglitazone maleate?
The molecular weight of Rosiglitazone maleate is 473.13 g/mol.
Where can I buy Rosiglitazone maleate?
You can request a quote for Rosiglitazone maleate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Rosiglitazone maleate?
Yes, KEHONG BIO provides custom synthesis services for Rosiglitazone maleate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.