(+)-Sibutramine
TL;DR: (+)-Sibutramine (CAS 154752-44-0) is a chemical compound with molecular formula C17H26ClN and molecular weight 279.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R)-1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine
Also Known As: (+)-Sibutramine, (R)-Sibutramine, sibutramine, R-(+)-Sibutramine, Sibutramine, (R)-
| Molecular Formula | C17H26ClN |
|---|---|
| Molecular Weight | 279.18 g/mol |
| LogP | 5.4 |
| Topological Polar Surface Area | 3.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 5 |
| Exact Mass | 279.17538 |
| Heavy Atoms | 19 |
| Complexity | 275.0 |
Chemical Identifiers
| CAS Number | 154752-44-0 |
|---|---|
| SMILES | CC(C)C[C@H](C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C |
| InChIKey | UNAANXDKBXWMLN-MRXNPFEDSA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
(+)-Sibutramine (CAS 154752-44-0), with molecular formula C17H26ClN and molecular weight 279.18 g/mol. IUPAC: (1R)-1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine.
Chemical Property Profile of (+)-Sibutramine
Property Insights of (+)-Sibutramine
The XLogP value of 5.4 indicates that (+)-Sibutramine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.2 Ų, (+)-Sibutramine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (+)-Sibutramine has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (+)-Sibutramine?
The CAS number of (+)-Sibutramine is 154752-44-0.
What is the molecular formula of (+)-Sibutramine?
The molecular formula of (+)-Sibutramine is C17H26ClN.
What is the molecular weight of (+)-Sibutramine?
The molecular weight of (+)-Sibutramine is 279.18 g/mol.
Where can I buy (+)-Sibutramine?
You can request a quote for (+)-Sibutramine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (+)-Sibutramine?
Yes, KEHONG BIO provides custom synthesis services for (+)-Sibutramine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.