ICE Inhibitor IV structure

ICE Inhibitor IV

TL;DR: ICE Inhibitor IV (CAS 154674-81-4) is a chemical compound with molecular formula C33H42N4O10 and molecular weight 654.29 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-5-(2,6-dimethylbenzoyl)oxy-4-oxopentanoic acid

Also Known As: ICE Inhibitor IV, Caspase-1 Inhibitor IV, BACMK, Boc-D-CMK, J1.079.219C

CAS: 154674-81-4
Molecular Formula C33H42N4O10
Molecular Weight 654.29 g/mol
LogP 1.08734
Topological Polar Surface Area 217.3 Ų
Hydrogen Bond Donors 6
Hydrogen Bond Acceptors 9
Rotatable Bonds 16
Exact Mass 654.2901
Heavy Atoms 47
Complexity 1468.4873

Chemical Identifiers

CAS Number 154674-81-4
SMILES CC1=C(C(=CC=C1)C)C(=O)OCC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)C

Product Overview

ICE Inhibitor IV (CAS 154674-81-4), with molecular formula C33H42N4O10 and molecular weight 654.29 g/mol. IUPAC: (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-5-(2,6-dimethylbenzoyl)oxy-4-oxopentanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of ICE Inhibitor IV

XLogP
1.08734
TPSA (Topological Polar Surface Area)
217.3
Hydrogen Bond Donors
6
Hydrogen Bond Acceptors
9
Rotatable Bonds
16
Heavy Atoms
47
Complexity
1468.4873
Exact Mass
654.2901
Monoisotopic Mass
654.2901
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of ICE Inhibitor IV

The XLogP value of 1.08734 suggests moderate lipophilicity, balancing water solubility and membrane permeability for ICE Inhibitor IV. The TPSA of 217.3 Ų indicates high polarity, suggesting ICE Inhibitor IV may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, ICE Inhibitor IV has 6 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of ICE Inhibitor IV?

The CAS number of ICE Inhibitor IV is 154674-81-4.

What is the molecular formula of ICE Inhibitor IV?

The molecular formula of ICE Inhibitor IV is C33H42N4O10.

What is the molecular weight of ICE Inhibitor IV?

The molecular weight of ICE Inhibitor IV is 654.29 g/mol.

Where can I buy ICE Inhibitor IV?

You can request a quote for ICE Inhibitor IV directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for ICE Inhibitor IV?

Yes, KEHONG BIO provides custom synthesis services for ICE Inhibitor IV and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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