![N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide structure](/static/products/1545/154563-52-7.webp)
N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide
TL;DR: N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide (CAS 154563-52-7) is a chemical compound with molecular formula C13H6ClF6N3O2 and molecular weight 385.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-N-[4-(trifluoromethoxy)phenyl]-4-(trifluoromethyl)pyrimidine-5-carboxamide
Also Known As: N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide, 2-chloro-N-[4-(trifluoromethoxy)phenyl]-4-(trifluoromethyl)pyrimidine-5-carboxamide, 2-chloro-4-trifluoromethyl-pyrimidine-5-carboxylic acid (4-trifluoromethoxy-phenyl)-amide, 2-Chloro-N-(4-(trifluoromethoxy)phenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide, 2-Chloro-N-[4-(trifluoromethoxy)phenyl]-4-(trifluoromethyl)-5-pyrimidinecarboxamide
| Molecular Formula | C13H6ClF6N3O2 |
|---|---|
| Molecular Weight | 385.01 g/mol |
| LogP | 4.2997 |
| Topological Polar Surface Area | 64.11 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 385.00528 |
| Heavy Atoms | 25 |
| Complexity | 776.8143 |
Chemical Identifiers
| CAS Number | 154563-52-7 |
|---|---|
| SMILES | C1=CC(=CC=C1NC(=O)C2=CN=C(N=C2C(F)(F)F)Cl)OC(F)(F)F |
Product Overview
N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide (CAS 154563-52-7), with molecular formula C13H6ClF6N3O2 and molecular weight 385.01 g/mol. IUPAC: 2-chloro-N-[4-(trifluoromethoxy)phenyl]-4-(trifluoromethyl)pyrimidine-5-carboxamide.
Chemical Property Profile of N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide
Property Insights of N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide
The XLogP value of 4.2997 indicates that N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.11 Ų falls within the moderate polarity range, balancing permeability and solubility for N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide. Following Lipinski's Rule of Five, N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide?
The CAS number of N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide is 154563-52-7.
What is the molecular formula of N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide?
The molecular formula of N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide is C13H6ClF6N3O2.
What is the molecular weight of N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide?
The molecular weight of N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide is 385.01 g/mol.
Where can I buy N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide?
You can request a quote for N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N5-[4-(trifluoromethoxy)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.