8-hydroxyquinolin-2(1H)-one
TL;DR: 8-hydroxyquinolin-2(1H)-one (CAS 15450-76-7) is a chemical compound with molecular formula C9H7NO2 and molecular weight 161.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-hydroxy-1H-quinolin-2-one
Also Known As: 2,8-Quinolinediol, quinoline-2,8-diol, 2,8-Dihydroxyquinoline, 8-Hydroxycarbostyril, 8-Hydroxycarbostyryl
| Molecular Formula | C9H7NO2 |
|---|---|
| Molecular Weight | 161.05 g/mol |
| LogP | 1.0 |
| Topological Polar Surface Area | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 161.04768 |
| Heavy Atoms | 12 |
| Complexity | 225.0 |
Chemical Identifiers
| CAS Number | 15450-76-7 |
|---|---|
| SMILES | C1=CC2=C(C(=C1)O)NC(=O)C=C2 |
| InChIKey | ZXZKYYHTWHJHFT-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 19 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
8-hydroxyquinolin-2(1H)-one (CAS 15450-76-7), with molecular formula C9H7NO2 and molecular weight 161.05 g/mol. IUPAC: 8-hydroxy-1H-quinolin-2-one.
Chemical Property Profile of 8-hydroxyquinolin-2(1H)-one
Property Insights of 8-hydroxyquinolin-2(1H)-one
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-hydroxyquinolin-2(1H)-one. With a topological polar surface area (TPSA) of 49.3 Ų, 8-hydroxyquinolin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-hydroxyquinolin-2(1H)-one has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-hydroxyquinolin-2(1H)-one?
The CAS number of 8-hydroxyquinolin-2(1H)-one is 15450-76-7.
What is the molecular formula of 8-hydroxyquinolin-2(1H)-one?
The molecular formula of 8-hydroxyquinolin-2(1H)-one is C9H7NO2.
What is the molecular weight of 8-hydroxyquinolin-2(1H)-one?
The molecular weight of 8-hydroxyquinolin-2(1H)-one is 161.05 g/mol.
Where can I buy 8-hydroxyquinolin-2(1H)-one?
You can request a quote for 8-hydroxyquinolin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-hydroxyquinolin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 8-hydroxyquinolin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.