Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine structure

Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine

TL;DR: Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine (CAS 15436-20-1) is a chemical compound with molecular formula C19H24FN4O12P and molecular weight 550.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(2R,3S,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl [(2R,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] hydrogen phosphate

Also Known As: Dtpdfu, KST-1A1683, Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine, thymidylyl-(3/'-5/')-2/'-deoxy-5-fluorouridine, Thymidine, 2'-deoxy-5-fluorouridyl-(5'-3')-

CAS: 15436-20-1
Molecular Formula C19H24FN4O12P
Molecular Weight 550.11 g/mol
LogP -3.2
Topological Polar Surface Area 214.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 13
Rotatable Bonds 8
Exact Mass 550.11127
Heavy Atoms 37
Complexity 1100.0

Chemical Identifiers

CAS Number 15436-20-1
SMILES CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)OP(=O)(O)OC[C@@H]3[C@H](C[C@@H](O3)N4C=C(C(=O)NC4=O)F)O
InChIKey IGJXAMJSWYEODZ-BBZRCZKMSA-N

Product Overview

Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine (CAS 15436-20-1), with molecular formula C19H24FN4O12P and molecular weight 550.11 g/mol. IUPAC: [(2R,3S,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl [(2R,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] hydrogen phosphate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine

XLogP
-3.2
TPSA (Topological Polar Surface Area)
214.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
13
Rotatable Bonds
8
Heavy Atoms
37
Complexity
1100.0
Exact Mass
550.11127
Monoisotopic Mass
550.11127
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine

The XLogP value of -3.2 indicates that Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 214.0 Ų indicates high polarity, suggesting Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine has 5 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine?

The CAS number of Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine is 15436-20-1.

What is the molecular formula of Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine?

The molecular formula of Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine is C19H24FN4O12P.

What is the molecular weight of Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine?

The molecular weight of Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine is 550.11 g/mol.

Where can I buy Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine?

You can request a quote for Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine?

Yes, KEHONG BIO provides custom synthesis services for Thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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