SQ-NHS structure

SQ-NHS

TL;DR: SQ-NHS (CAS 154161-81-6) is a chemical compound with molecular formula C34H32ClN3O6 and molecular weight 613.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-[(5-chloro-1,3,3-trimethylindol-1-ium-2-yl)methylidene]-2-[[5-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-1-ethyl-3,3-dimethylindol-2-ylidene]methyl]-3-oxocyclobuten-1-olate

Also Known As: SQ-NHS, SQ-NHS*, 4-[(5-chloro-1,3,3-trimethylindol-1-ium-2-yl)methylidene]-2-[[5-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-1-ethyl-3,3-dimethylindol-2-ylidene]methyl]-3-oxocyclobuten-1-olate, SQUARAIN-CARBOXYLATE N-SUCCINIMIDYL ESTER, 4-[(5-Chloro-1,3,3-trimethyl-3H-indol-1-ium-2-yl)methylidene]-2-[(5-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}-1-ethyl-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene)methyl]-3-oxocyclobut-1-en-1-olate

CAS: 154161-81-6
Molecular Formula C34H32ClN3O6
Molecular Weight 613.20 g/mol
LogP 4.3919
Topological Polar Surface Area 110.06 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 613.19794
Heavy Atoms 44
Complexity 1828.4327

Chemical Identifiers

CAS Number 154161-81-6
SMILES CCN1C2=C(C=C(C=C2)C(=O)ON3C(=O)CCC3=O)C(C1=CC4=C(C(=CC5=[N+](C6=C(C5(C)C)C=C(C=C6)Cl)C)C4=O)[O-])(C)C

Product Overview

SQ-NHS (CAS 154161-81-6), with molecular formula C34H32ClN3O6 and molecular weight 613.20 g/mol. IUPAC: 4-[(5-chloro-1,3,3-trimethylindol-1-ium-2-yl)methylidene]-2-[[5-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-1-ethyl-3,3-dimethylindol-2-ylidene]methyl]-3-oxocyclobuten-1-olate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of SQ-NHS

XLogP
4.3919
TPSA (Topological Polar Surface Area)
110.06
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
44
Complexity
1828.4327
Exact Mass
613.19794
Monoisotopic Mass
613.19794
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of SQ-NHS

The XLogP value of 4.3919 indicates that SQ-NHS is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.06 Ų falls within the moderate polarity range, balancing permeability and solubility for SQ-NHS. Following Lipinski's Rule of Five, SQ-NHS has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of SQ-NHS?

The CAS number of SQ-NHS is 154161-81-6.

What is the molecular formula of SQ-NHS?

The molecular formula of SQ-NHS is C34H32ClN3O6.

What is the molecular weight of SQ-NHS?

The molecular weight of SQ-NHS is 613.20 g/mol.

Where can I buy SQ-NHS?

You can request a quote for SQ-NHS directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for SQ-NHS?

Yes, KEHONG BIO provides custom synthesis services for SQ-NHS and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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