6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid
TL;DR: 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid (CAS 153758-25-9) is a chemical compound with molecular formula C8H11F3N2O5 and molecular weight 272.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S,4S,5R,6R)-4,5-dihydroxy-6-[(2,2,2-trifluoroacetyl)amino]piperidine-3-carboxylic acid
Also Known As: Heparastatin, Heparastatin Hydrochloride, 6-TFA-4,5-DHPC, 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid, 153758-25-9 (as a salt free form)
| Molecular Formula | C8H11F3N2O5 |
|---|---|
| Molecular Weight | 272.06 g/mol |
| LogP | -3.3 |
| Topological Polar Surface Area | 119.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 2 |
| Exact Mass | 272.062 |
| Heavy Atoms | 18 |
| Complexity | 348.0 |
Chemical Identifiers
| CAS Number | 153758-25-9 |
|---|---|
| SMILES | C1[C@@H]([C@@H]([C@@H]([C@H](N1)NC(=O)C(F)(F)F)O)O)C(=O)O |
| InChIKey | UOPZEWVVILIZJY-NEEWWZBLSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid (CAS 153758-25-9), with molecular formula C8H11F3N2O5 and molecular weight 272.06 g/mol. IUPAC: (3S,4S,5R,6R)-4,5-dihydroxy-6-[(2,2,2-trifluoroacetyl)amino]piperidine-3-carboxylic acid.
Chemical Property Profile of 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid
Property Insights of 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid
The XLogP value of -3.3 indicates that 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 119.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid. Following Lipinski's Rule of Five, 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid has 5 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid?
The CAS number of 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid is 153758-25-9.
What is the molecular formula of 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid?
The molecular formula of 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid is C8H11F3N2O5.
What is the molecular weight of 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid?
The molecular weight of 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid is 272.06 g/mol.
Where can I buy 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid?
You can request a quote for 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 6-(Trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.