3'-F-Dtfp
TL;DR: 3'-F-Dtfp (CAS 152829-59-9) is a chemical compound with molecular formula C10H13F2N2O6P and molecular weight 326.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
fluoro-[[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphinic acid
Also Known As: 3'-F-Dtfp, 3'-Fluoro-3'-deoxythymidine-5'-fluorophosphate, 3'-Fluoro-3'-deoxythymidine-5'-phosphorofluoridate, fluoro-[[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy]phosphinic acid, fluoro-[[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphinic acid
| Molecular Formula | C10H13F2N2O6P |
|---|---|
| Molecular Weight | 326.05 g/mol |
| LogP | 0.55712 |
| Topological Polar Surface Area | 110.62 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 326.04794 |
| Heavy Atoms | 21 |
| Complexity | 682.8609 |
Chemical Identifiers
| CAS Number | 152829-59-9 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)F)F |
Product Overview
3'-F-Dtfp (CAS 152829-59-9), with molecular formula C10H13F2N2O6P and molecular weight 326.05 g/mol. IUPAC: fluoro-[[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphinic acid.
Chemical Property Profile of 3'-F-Dtfp
Property Insights of 3'-F-Dtfp
The XLogP value of 0.55712 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3'-F-Dtfp. The TPSA of 110.62 Ų falls within the moderate polarity range, balancing permeability and solubility for 3'-F-Dtfp. Following Lipinski's Rule of Five, 3'-F-Dtfp has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-F-Dtfp?
The CAS number of 3'-F-Dtfp is 152829-59-9.
What is the molecular formula of 3'-F-Dtfp?
The molecular formula of 3'-F-Dtfp is C10H13F2N2O6P.
What is the molecular weight of 3'-F-Dtfp?
The molecular weight of 3'-F-Dtfp is 326.05 g/mol.
Where can I buy 3'-F-Dtfp?
You can request a quote for 3'-F-Dtfp directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-F-Dtfp?
Yes, KEHONG BIO provides custom synthesis services for 3'-F-Dtfp and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.