TLK117
TL;DR: TLK117 (CAS 152684-53-2) is a chemical compound with molecular formula C23H27N3O6S and molecular weight 473.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-amino-5-[[(2R)-3-benzylsulfanyl-1-[[(R)-carboxy(phenyl)methyl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Also Known As: TLK117, GLU-BCS-PGY, 10gs, TER117, TLK 117
| Molecular Formula | C23H27N3O6S |
|---|---|
| Molecular Weight | 473.16 g/mol |
| LogP | -0.9 |
| Topological Polar Surface Area | 184.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 13 |
| Exact Mass | 473.16205 |
| Heavy Atoms | 33 |
| Complexity | 665.0 |
Chemical Identifiers
| CAS Number | 152684-53-2 |
|---|---|
| SMILES | C1=CC=C(C=C1)CSC[C@@H](C(=O)N[C@H](C2=CC=CC=C2)C(=O)O)NC(=O)CC[C@@H](C(=O)O)N |
| InChIKey | ZPSKWMFLCHMEOY-CMKODMSKSA-N |
Product Overview
TLK117 (CAS 152684-53-2), with molecular formula C23H27N3O6S and molecular weight 473.16 g/mol. IUPAC: (2S)-2-amino-5-[[(2R)-3-benzylsulfanyl-1-[[(R)-carboxy(phenyl)methyl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid.
Chemical Property Profile of TLK117
Property Insights of TLK117
The XLogP value of -0.9 indicates that TLK117 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 184.0 Ų indicates high polarity, suggesting TLK117 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, TLK117 has 5 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of TLK117?
The CAS number of TLK117 is 152684-53-2.
What is the molecular formula of TLK117?
The molecular formula of TLK117 is C23H27N3O6S.
What is the molecular weight of TLK117?
The molecular weight of TLK117 is 473.16 g/mol.
Where can I buy TLK117?
You can request a quote for TLK117 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for TLK117?
Yes, KEHONG BIO provides custom synthesis services for TLK117 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.