Cortexolone
TL;DR: Cortexolone (CAS 152-58-9) is a chemical compound with molecular formula C21H30O4 and molecular weight 346.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: Cortexolone, CORTODOXONE, Reichstein S, Substance S, 11-Dioxycortisol
| Molecular Formula | C21H30O4 |
|---|---|
| Molecular Weight | 346.21 g/mol |
| LogP | 2.5 |
| Topological Polar Surface Area | 74.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 346.21442 |
| Heavy Atoms | 25 |
| Complexity | 652.0 |
Chemical Identifiers
| CAS Number | 152-58-9 |
|---|---|
| SMILES | CC12CCC(=O)C=C1CCC3C2CCC4(C3CC[C@@]4(C(=O)CO)O)C |
| InChIKey | WHBHBVVOGNECLV-VLAJLFEZSA-N |
Product Overview
Cortexolone (CAS 152-58-9), with molecular formula C21H30O4 and molecular weight 346.21 g/mol. IUPAC: (17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of Cortexolone
Property Insights of Cortexolone
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Cortexolone. The TPSA of 74.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Cortexolone. Following Lipinski's Rule of Five, Cortexolone has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Cortexolone?
The CAS number of Cortexolone is 152-58-9.
What is the molecular formula of Cortexolone?
The molecular formula of Cortexolone is C21H30O4.
What is the molecular weight of Cortexolone?
The molecular weight of Cortexolone is 346.21 g/mol.
Where can I buy Cortexolone?
You can request a quote for Cortexolone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Cortexolone?
Yes, KEHONG BIO provides custom synthesis services for Cortexolone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.