Cholestan-6-oxo-3,5-diol structure

Cholestan-6-oxo-3,5-diol

TL;DR: Cholestan-6-oxo-3,5-diol (CAS 15167-22-3) is a chemical compound with molecular formula C27H46O3 and molecular weight 418.34 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3S,5R,8S,9S,10R,13R,14S,17R)-3,5-dihydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-one

Also Known As: Yakkasterone, cholestan-6-oxo-3,5-diol, 6-Oxo-3,5-diol, A-hydroxy-6-keto Cholesterol, 5-Hydroxy-6-keto cholesterol

CAS: 15167-22-3
Molecular Formula C27H46O3
Molecular Weight 418.34 g/mol
LogP 7.0
Topological Polar Surface Area 57.5 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 3
Rotatable Bonds 5
Exact Mass 418.3447
Heavy Atoms 30
Complexity 658.0

Chemical Identifiers

CAS Number 15167-22-3
SMILES C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC(=O)[C@@]4([C@@]3(CC[C@@H](C4)O)C)O)C
InChIKey SJZZRXMQSAXCFD-ZCBMJONGSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (2 patents) Pharmaceutical Intermediates (2 patents)

Product Overview

Cholestan-6-oxo-3,5-diol (CAS 15167-22-3), with molecular formula C27H46O3 and molecular weight 418.34 g/mol. IUPAC: (3S,5R,8S,9S,10R,13R,14S,17R)-3,5-dihydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Cholestan-6-oxo-3,5-diol

XLogP
7.0
TPSA (Topological Polar Surface Area)
57.5
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
Rotatable Bonds
5
Heavy Atoms
30
Complexity
658.0
Exact Mass
418.3447
Monoisotopic Mass
418.3447
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Cholestan-6-oxo-3,5-diol

The XLogP value of 7.0 indicates that Cholestan-6-oxo-3,5-diol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.5 Ų, Cholestan-6-oxo-3,5-diol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Cholestan-6-oxo-3,5-diol has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Cholestan-6-oxo-3,5-diol?

The CAS number of Cholestan-6-oxo-3,5-diol is 15167-22-3.

What is the molecular formula of Cholestan-6-oxo-3,5-diol?

The molecular formula of Cholestan-6-oxo-3,5-diol is C27H46O3.

What is the molecular weight of Cholestan-6-oxo-3,5-diol?

The molecular weight of Cholestan-6-oxo-3,5-diol is 418.34 g/mol.

Where can I buy Cholestan-6-oxo-3,5-diol?

You can request a quote for Cholestan-6-oxo-3,5-diol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Cholestan-6-oxo-3,5-diol?

Yes, KEHONG BIO provides custom synthesis services for Cholestan-6-oxo-3,5-diol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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