6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine
TL;DR: 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine (CAS 150863-84-6) is a chemical compound with molecular formula C10H10ClFN4O3 and molecular weight 288.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,3R,4R,5R)-5-(6-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
Also Known As: 6-Cl-9-Dfr-purine, 6Cl2'F-PurdR, 6-Chloro-9-(2-deoxy-2-fluororibofuranosyl)purine, 6-chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)purine, (2R,3R,4R,5R)-5-(6-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
| Molecular Formula | C10H10ClFN4O3 |
|---|---|
| Molecular Weight | 288.04 g/mol |
| LogP | 1.3 |
| Topological Polar Surface Area | 93.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 288.04254 |
| Heavy Atoms | 19 |
| Complexity | 342.0 |
Chemical Identifiers
| CAS Number | 150863-84-6 |
|---|---|
| SMILES | C1=NC2=C(C(=N1)Cl)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F |
| InChIKey | HLXISARTQIJHHE-QYYRPYCUSA-N |
Product Overview
6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine (CAS 150863-84-6), with molecular formula C10H10ClFN4O3 and molecular weight 288.04 g/mol. IUPAC: (2R,3R,4R,5R)-5-(6-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol.
Chemical Property Profile of 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine
Property Insights of 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine. The TPSA of 93.3 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine. Following Lipinski's Rule of Five, 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine?
The CAS number of 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine is 150863-84-6.
What is the molecular formula of 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine?
The molecular formula of 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine is C10H10ClFN4O3.
What is the molecular weight of 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine?
The molecular weight of 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine is 288.04 g/mol.
Where can I buy 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine?
You can request a quote for 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine?
Yes, KEHONG BIO provides custom synthesis services for 6-Chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.