瑞替加滨
TL;DR: 瑞替加滨 (CAS 150812-12-7) is a chemical compound with molecular formula C16H18FN3O2 and molecular weight 303.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
瑞替加滨
ethyl N-[2-amino-4-[(4-fluorophenyl)methylamino]phenyl]carbamate
Also Known As: Retigabine, Ezogabine, Potiga, Trobalt, Retigabina
| Molecular Formula | C16H18FN3O2 |
|---|---|
| Molecular Weight | 303.14 g/mol |
| LogP | 2.8 |
| Topological Polar Surface Area | 76.4 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 303.1383 |
| Heavy Atoms | 22 |
| Complexity | 348.0 |
| Melting Point | 138-145 °C |
| Solubility | At room temperature ... practically insoluble in aqueous media above pH4, while the solubility is higher in polar organic solvents |
Chemical Identifiers
| CAS Number | 150812-12-7 |
|---|---|
| SMILES | CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N |
| InChIKey | PCOBBVZJEWWZFR-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
瑞替加滨 (CAS 150812-12-7), with molecular formula C16H18FN3O2 and molecular weight 303.14 g/mol. IUPAC: ethyl N-[2-amino-4-[(4-fluorophenyl)methylamino]phenyl]carbamate.
Chemical Property Profile of 瑞替加滨
Property Insights of 瑞替加滨
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 瑞替加滨. The TPSA of 76.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 瑞替加滨. Following Lipinski's Rule of Five, 瑞替加滨 has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 瑞替加滨?
The CAS number of 瑞替加滨 is 150812-12-7.
What is the molecular formula of 瑞替加滨?
The molecular formula of 瑞替加滨 is C16H18FN3O2.
What is the molecular weight of 瑞替加滨?
The molecular weight of 瑞替加滨 is 303.14 g/mol.
Where can I buy 瑞替加滨?
You can request a quote for 瑞替加滨 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 瑞替加滨?
Yes, KEHONG BIO provides custom synthesis services for 瑞替加滨 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.