Efletirizine
TL;DR: Efletirizine (CAS 150756-35-7) is a chemical compound with molecular formula C21H24F2N2O3 and molecular weight 390.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[2-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]ethoxy]acetic acid
Also Known As: Efletirizine, efletirizina, efletirizinum, Efletirizine [INN], Efletirizine < Rec INN
| Molecular Formula | C21H24F2N2O3 |
|---|---|
| Molecular Weight | 390.18 g/mol |
| LogP | 1.3 |
| Topological Polar Surface Area | 53.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 390.1755 |
| Heavy Atoms | 28 |
| Complexity | 450.0 |
Chemical Identifiers
| CAS Number | 150756-35-7 |
|---|---|
| SMILES | C1CN(CCN1CCOCC(=O)O)C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F |
| InChIKey | BAWMMJAUVBLLEE-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Efletirizine (CAS 150756-35-7), with molecular formula C21H24F2N2O3 and molecular weight 390.18 g/mol. IUPAC: 2-[2-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]ethoxy]acetic acid.
Chemical Property Profile of Efletirizine
Property Insights of Efletirizine
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Efletirizine. With a topological polar surface area (TPSA) of 53.0 Ų, Efletirizine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Efletirizine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Efletirizine?
The CAS number of Efletirizine is 150756-35-7.
What is the molecular formula of Efletirizine?
The molecular formula of Efletirizine is C21H24F2N2O3.
What is the molecular weight of Efletirizine?
The molecular weight of Efletirizine is 390.18 g/mol.
Where can I buy Efletirizine?
You can request a quote for Efletirizine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Efletirizine?
Yes, KEHONG BIO provides custom synthesis services for Efletirizine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.