8-Bromoguanosino-3',5'-cyclic monophosphorothioate
TL;DR: 8-Bromoguanosino-3',5'-cyclic monophosphorothioate (CAS 150418-07-8) is a chemical compound with molecular formula C10H11BrN5O6PS and molecular weight 438.94 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,5R)-2-(2-amino-8-bromopurin-9-yl)-5-(dihydroxyphosphinothioyloxymethyl)-2,5-dihydrofuran-3,4-diol
Also Known As: 8-Br-Cgmps, SID:85083170, 8-Bromoguanosino-3',5'-cyclic monophosphorothioate, (2R,5R)-2-(2-amino-8-bromopurin-9-yl)-5-(dihydroxyphosphinothioyloxymethyl)-2,5-dihydrofuran-3,4-diol, (R)-8-Bromoguanosine cyclic 3',5'-(hydrogen phosphorothioate)
| Molecular Formula | C10H11BrN5O6PS |
|---|---|
| Molecular Weight | 438.94 g/mol |
| LogP | 0.6217 |
| Topological Polar Surface Area | 169.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 438.9351 |
| Heavy Atoms | 24 |
| Complexity | 883.991 |
Chemical Identifiers
| CAS Number | 150418-07-8 |
|---|---|
| SMILES | C1=C2C(=NC(=N1)N)N(C(=N2)Br)[C@H]3C(=C([C@H](O3)COP(=S)(O)O)O)O |
Product Overview
8-Bromoguanosino-3',5'-cyclic monophosphorothioate (CAS 150418-07-8), with molecular formula C10H11BrN5O6PS and molecular weight 438.94 g/mol. IUPAC: (2R,5R)-2-(2-amino-8-bromopurin-9-yl)-5-(dihydroxyphosphinothioyloxymethyl)-2,5-dihydrofuran-3,4-diol.
Chemical Property Profile of 8-Bromoguanosino-3',5'-cyclic monophosphorothioate
Property Insights of 8-Bromoguanosino-3',5'-cyclic monophosphorothioate
The XLogP value of 0.6217 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-Bromoguanosino-3',5'-cyclic monophosphorothioate. The TPSA of 169.0 Ų indicates high polarity, suggesting 8-Bromoguanosino-3',5'-cyclic monophosphorothioate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 8-Bromoguanosino-3',5'-cyclic monophosphorothioate has 5 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-Bromoguanosino-3',5'-cyclic monophosphorothioate?
The CAS number of 8-Bromoguanosino-3',5'-cyclic monophosphorothioate is 150418-07-8.
What is the molecular formula of 8-Bromoguanosino-3',5'-cyclic monophosphorothioate?
The molecular formula of 8-Bromoguanosino-3',5'-cyclic monophosphorothioate is C10H11BrN5O6PS.
What is the molecular weight of 8-Bromoguanosino-3',5'-cyclic monophosphorothioate?
The molecular weight of 8-Bromoguanosino-3',5'-cyclic monophosphorothioate is 438.94 g/mol.
Where can I buy 8-Bromoguanosino-3',5'-cyclic monophosphorothioate?
You can request a quote for 8-Bromoguanosino-3',5'-cyclic monophosphorothioate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-Bromoguanosino-3',5'-cyclic monophosphorothioate?
Yes, KEHONG BIO provides custom synthesis services for 8-Bromoguanosino-3',5'-cyclic monophosphorothioate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.