17-Dimethylaminogeldanamycin
TL;DR: 17-Dimethylaminogeldanamycin (CAS 150270-08-9) is a chemical compound with molecular formula C32H48N4O8 and molecular weight 616.35 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[19-[2-(dimethylamino)ethylamino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate
Also Known As: alvespimycin, 17-DMAG, 17-Dimethylaminogeldanamycin, 17-(DIMETHYLAMINOETHYLAMINO)-17-DEMETHOXYGELDANAMYCIN HCL, KOS 1022; KOS-1022; KOS1022; 17-DMAG;150270-08-9
| Molecular Formula | C32H48N4O8 |
|---|---|
| Molecular Weight | 616.35 g/mol |
| LogP | 1.9132 |
| Topological Polar Surface Area | 169.52 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 7 |
| Exact Mass | 616.3472 |
| Heavy Atoms | 44 |
| Complexity | 1232.4777 |
Chemical Identifiers
| CAS Number | 150270-08-9 |
|---|---|
| SMILES | CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCCN(C)C)C)OC)OC(=O)N)C)C)O)OC |
Product Overview
17-Dimethylaminogeldanamycin (CAS 150270-08-9), with molecular formula C32H48N4O8 and molecular weight 616.35 g/mol. IUPAC: [19-[2-(dimethylamino)ethylamino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate.
Chemical Property Profile of 17-Dimethylaminogeldanamycin
Property Insights of 17-Dimethylaminogeldanamycin
The XLogP value of 1.9132 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 17-Dimethylaminogeldanamycin. The TPSA of 169.52 Ų indicates high polarity, suggesting 17-Dimethylaminogeldanamycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 17-Dimethylaminogeldanamycin has 4 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 17-Dimethylaminogeldanamycin?
The CAS number of 17-Dimethylaminogeldanamycin is 150270-08-9.
What is the molecular formula of 17-Dimethylaminogeldanamycin?
The molecular formula of 17-Dimethylaminogeldanamycin is C32H48N4O8.
What is the molecular weight of 17-Dimethylaminogeldanamycin?
The molecular weight of 17-Dimethylaminogeldanamycin is 616.35 g/mol.
Where can I buy 17-Dimethylaminogeldanamycin?
You can request a quote for 17-Dimethylaminogeldanamycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 17-Dimethylaminogeldanamycin?
Yes, KEHONG BIO provides custom synthesis services for 17-Dimethylaminogeldanamycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.