GR 144053
TL;DR: GR 144053 (CAS 150040-22-5) is a chemical compound with molecular formula C18H27N5O2 and molecular weight 345.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[4-(4-carbamimidoylphenyl)piperazin-1-yl]piperidin-1-yl]acetic acid
Also Known As: GR 144053 trihydrochloride, GR 144053, GR-144053F, 2-[4-[4-(4-carbamimidoylphenyl)piperazin-1-yl]piperidin-1-yl]acetic acid, BRD-K12120659-305-01-4
| Molecular Formula | C18H27N5O2 |
|---|---|
| Molecular Weight | 345.22 g/mol |
| LogP | -1.3 |
| Topological Polar Surface Area | 96.9 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 345.21646 |
| Heavy Atoms | 25 |
| Complexity | 462.0 |
Chemical Identifiers
| CAS Number | 150040-22-5 |
|---|---|
| SMILES | C1CN(CCC1N2CCN(CC2)C3=CC=C(C=C3)C(=N)N)CC(=O)O |
| InChIKey | QGEGSJUSWLLZLH-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
GR 144053 (CAS 150040-22-5), with molecular formula C18H27N5O2 and molecular weight 345.22 g/mol. IUPAC: 2-[4-[4-(4-carbamimidoylphenyl)piperazin-1-yl]piperidin-1-yl]acetic acid.
Chemical Property Profile of GR 144053
Property Insights of GR 144053
The XLogP value of -1.3 indicates that GR 144053 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 96.9 Ų falls within the moderate polarity range, balancing permeability and solubility for GR 144053. Following Lipinski's Rule of Five, GR 144053 has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of GR 144053?
The CAS number of GR 144053 is 150040-22-5.
What is the molecular formula of GR 144053?
The molecular formula of GR 144053 is C18H27N5O2.
What is the molecular weight of GR 144053?
The molecular weight of GR 144053 is 345.22 g/mol.
Where can I buy GR 144053?
You can request a quote for GR 144053 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for GR 144053?
Yes, KEHONG BIO provides custom synthesis services for GR 144053 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.