Lurtotecan
TL;DR: Lurtotecan (CAS 149882-10-0) is a chemical compound with molecular formula C28H30N4O6 and molecular weight 518.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(18S)-18-ethyl-18-hydroxy-2-[(4-methylpiperazin-1-yl)methyl]-6,9,20-trioxa-13,24-diazahexacyclo[12.11.0.03,12.05,10.015,24.017,22]pentacosa-1,3,5(10),11,13,15,17(22)-heptaene-19,23-dione
Also Known As: Lurtotecan, Lurtotecan [INN], lurtotecanum, lurtotecan liposome, Liposomal lurtotecan
| Molecular Formula | C28H30N4O6 |
|---|---|
| Molecular Weight | 518.22 g/mol |
| LogP | 0.3 |
| Topological Polar Surface Area | 105.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 3 |
| Exact Mass | 518.21655 |
| Heavy Atoms | 38 |
| Complexity | 1070.0 |
Chemical Identifiers
| CAS Number | 149882-10-0 |
|---|---|
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC6=C(C=C5N=C4C3=C2)OCCO6)CN7CCN(CC7)C)O |
| InChIKey | RVFGKBWWUQOIOU-NDEPHWFRSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lurtotecan (CAS 149882-10-0), with molecular formula C28H30N4O6 and molecular weight 518.22 g/mol. IUPAC: (18S)-18-ethyl-18-hydroxy-2-[(4-methylpiperazin-1-yl)methyl]-6,9,20-trioxa-13,24-diazahexacyclo[12.11.0.03,12.05,10.015,24.017,22]pentacosa-1,3,5(10),11,13,15,17(22)-heptaene-19,23-dione.
Chemical Property Profile of Lurtotecan
Property Insights of Lurtotecan
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Lurtotecan. The TPSA of 105.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Lurtotecan. Following Lipinski's Rule of Five, Lurtotecan has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lurtotecan?
The CAS number of Lurtotecan is 149882-10-0.
What is the molecular formula of Lurtotecan?
The molecular formula of Lurtotecan is C28H30N4O6.
What is the molecular weight of Lurtotecan?
The molecular weight of Lurtotecan is 518.22 g/mol.
Where can I buy Lurtotecan?
You can request a quote for Lurtotecan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lurtotecan?
Yes, KEHONG BIO provides custom synthesis services for Lurtotecan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.