Loe 908
TL;DR: Loe 908 (CAS 149759-26-2) is a chemical compound with molecular formula C41H48N2O9 and molecular weight 712.34 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)-2-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]acetamide
Also Known As: pinokalantum, LOE 908 hydrochloride, Pinokalant [INN], LOE 908, LOE-908;LOE908;LOE 908
| Molecular Formula | C41H48N2O9 |
|---|---|
| Molecular Weight | 712.34 g/mol |
| LogP | 6.6 |
| Topological Polar Surface Area | 107.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 17 |
| Exact Mass | 712.336 |
| Heavy Atoms | 52 |
| Complexity | 1060.0 |
Chemical Identifiers
| CAS Number | 149759-26-2 |
|---|---|
| SMILES | COC1=C(C(=C(C=C1)CCN(CCC2=C(C(=C(C=C2)OC)OC)OC)C(=O)C(C3=CC=CC=C3)C4=NCCC5=CC(=C(C=C54)OC)OC)OC)OC |
| InChIKey | PYWYBTRACMRUQV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Loe 908 (CAS 149759-26-2), with molecular formula C41H48N2O9 and molecular weight 712.34 g/mol. IUPAC: 2-(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)-2-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]acetamide.
Chemical Property Profile of Loe 908
Property Insights of Loe 908
The XLogP value of 6.6 indicates that Loe 908 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 107.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Loe 908. Following Lipinski's Rule of Five, Loe 908 has 0 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Loe 908?
The CAS number of Loe 908 is 149759-26-2.
What is the molecular formula of Loe 908?
The molecular formula of Loe 908 is C41H48N2O9.
What is the molecular weight of Loe 908?
The molecular weight of Loe 908 is 712.34 g/mol.
Where can I buy Loe 908?
You can request a quote for Loe 908 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Loe 908?
Yes, KEHONG BIO provides custom synthesis services for Loe 908 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.