(R,R)-Palonosetron
TL;DR: (R,R)-Palonosetron (CAS 149654-00-2) is a chemical compound with molecular formula C19H24N2O and molecular weight 296.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(1-azabicyclo[2.2.2]octan-3-yl)-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one
Also Known As: Palonosetron, (R,R)-Palonosetron, Palonosetron, (3R)-, (R,R)-Palonosetron Hydrochloride, 1H-Benz[de]isoquinolin-1-one, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-
| Molecular Formula | C19H24N2O |
|---|---|
| Molecular Weight | 296.19 g/mol |
| LogP | 2.6565 |
| Topological Polar Surface Area | 23.55 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 296.18887 |
| Heavy Atoms | 22 |
| Complexity | 617.86127 |
Chemical Identifiers
| CAS Number | 149654-00-2 |
|---|---|
| SMILES | C1CC2CN(C(=O)C3=CC=CC(=C23)C1)C4CN5CCC4CC5 |
Product Overview
(R,R)-Palonosetron (CAS 149654-00-2), with molecular formula C19H24N2O and molecular weight 296.19 g/mol. IUPAC: 2-(1-azabicyclo[2.2.2]octan-3-yl)-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one.
Chemical Property Profile of (R,R)-Palonosetron
Property Insights of (R,R)-Palonosetron
The XLogP value of 2.6565 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (R,R)-Palonosetron. With a topological polar surface area (TPSA) of 23.55 Ų, (R,R)-Palonosetron exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (R,R)-Palonosetron has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (R,R)-Palonosetron?
The CAS number of (R,R)-Palonosetron is 149654-00-2.
What is the molecular formula of (R,R)-Palonosetron?
The molecular formula of (R,R)-Palonosetron is C19H24N2O.
What is the molecular weight of (R,R)-Palonosetron?
The molecular weight of (R,R)-Palonosetron is 296.19 g/mol.
Where can I buy (R,R)-Palonosetron?
You can request a quote for (R,R)-Palonosetron directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (R,R)-Palonosetron?
Yes, KEHONG BIO provides custom synthesis services for (R,R)-Palonosetron and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.