dorzolamide
TL;DR: dorzolamide (CAS 149249-72-9) is a chemical compound with molecular formula C10H16N2O4S3 and molecular weight 324.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
Also Known As: dorzolamide, Dorzolamide impurity B, Dorzolamide, (+/-)-(cis)-, rac-cis Dorzolamide, (4R)-Dorzolamide
| Molecular Formula | C10H16N2O4S3 |
|---|---|
| Molecular Weight | 324.03 g/mol |
| LogP | 0.612 |
| Topological Polar Surface Area | 106.33 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 324.02722 |
| Heavy Atoms | 19 |
| Complexity | 690.357 |
Chemical Identifiers
| CAS Number | 149249-72-9 |
|---|---|
| SMILES | CCN[C@@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C |
Product Overview
dorzolamide (CAS 149249-72-9), with molecular formula C10H16N2O4S3 and molecular weight 324.03 g/mol. IUPAC: (4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide.
Chemical Property Profile of dorzolamide
Property Insights of dorzolamide
The XLogP value of 0.612 suggests moderate lipophilicity, balancing water solubility and membrane permeability for dorzolamide. The TPSA of 106.33 Ų falls within the moderate polarity range, balancing permeability and solubility for dorzolamide. Following Lipinski's Rule of Five, dorzolamide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of dorzolamide?
The CAS number of dorzolamide is 149249-72-9.
What is the molecular formula of dorzolamide?
The molecular formula of dorzolamide is C10H16N2O4S3.
What is the molecular weight of dorzolamide?
The molecular weight of dorzolamide is 324.03 g/mol.
Where can I buy dorzolamide?
You can request a quote for dorzolamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for dorzolamide?
Yes, KEHONG BIO provides custom synthesis services for dorzolamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.