Zeneca ZM 224832 structure

Zeneca ZM 224832

TL;DR: Zeneca ZM 224832 (CAS 149034-80-0) is a chemical compound with molecular formula C22H31BrClN7O2 and molecular weight 539.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3,5-diamino-N-[2-[2-[(6-bromo-5-hydroxy-1,1-dimethyl-2,3-dihydroinden-4-yl)methylamino]ethyl-methylamino]ethyl]-6-chloropyrazine-2-carboxamide

Also Known As: Zeneca ZM 224832, Zeneca ZM-224,832, ZENECA ZM224,832, ZENECA-ZM-224832, 3,5-diamino-N-[2-[2-[(6-bromo-5-hydroxy-1,1-dimethyl-2,3-dihydroinden-4-yl)methylamino]ethyl-methylamino]ethyl]-6-chloropyrazine-2-carboxamide

CAS: 149034-80-0
Molecular Formula C22H31BrClN7O2
Molecular Weight 539.14 g/mol
LogP 3.9
Topological Polar Surface Area 142.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 8
Rotatable Bonds 9
Exact Mass 539.1411
Heavy Atoms 33
Complexity 660.0

Chemical Identifiers

CAS Number 149034-80-0
SMILES CC1(CCC2=C(C(=C(C=C21)Br)O)CNCCN(C)CCNC(=O)C3=C(N=C(C(=N3)Cl)N)N)C
InChIKey MHIZNYQKJOLUQY-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (5 patents) Pharmaceutical Intermediates (2 patents)

Product Overview

Zeneca ZM 224832 (CAS 149034-80-0), with molecular formula C22H31BrClN7O2 and molecular weight 539.14 g/mol. IUPAC: 3,5-diamino-N-[2-[2-[(6-bromo-5-hydroxy-1,1-dimethyl-2,3-dihydroinden-4-yl)methylamino]ethyl-methylamino]ethyl]-6-chloropyrazine-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Zeneca ZM 224832

XLogP
3.9
TPSA (Topological Polar Surface Area)
142.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
8
Rotatable Bonds
9
Heavy Atoms
33
Complexity
660.0
Exact Mass
539.1411
Monoisotopic Mass
539.1411
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Zeneca ZM 224832

The XLogP value of 3.9 indicates that Zeneca ZM 224832 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 142.0 Ų indicates high polarity, suggesting Zeneca ZM 224832 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Zeneca ZM 224832 has 5 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Zeneca ZM 224832?

The CAS number of Zeneca ZM 224832 is 149034-80-0.

What is the molecular formula of Zeneca ZM 224832?

The molecular formula of Zeneca ZM 224832 is C22H31BrClN7O2.

What is the molecular weight of Zeneca ZM 224832?

The molecular weight of Zeneca ZM 224832 is 539.14 g/mol.

Where can I buy Zeneca ZM 224832?

You can request a quote for Zeneca ZM 224832 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Zeneca ZM 224832?

Yes, KEHONG BIO provides custom synthesis services for Zeneca ZM 224832 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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